DE SANTIS, SARA
DE SANTIS, SARA
DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Assegnisti
Unstable major molecular response as a trigger for next generation sequencing-based BCR::ABL1 mutation testing in chronic myeloid leukemia
2024 Benesova, A.; De Santis, S.; Polivkova, V.; Pecherkova, P.; Krizkova, J.; Suchankova, P.; Monaldi, C.; Klamova, H.; Srbova, D.; Zizkova, H.; Hochhaus, A.; Soverini, S.; Machova Polakova, K.
Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights
2023 Iezza M.; Cortesi S.; Ottaviani E.; Mancini M.; Venturi C.; Monaldi C.; De Santis S.; Testoni N.; Soverini S.; Rosti G.; Cavo M.; Castagnetti F.
SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted
2023 Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L.; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S.
CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors
2022 de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polakova K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S.
Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells
2022 Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.; Cavo M.; Soverini S.
Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia
2022 Soverini S.; De Santis S.; Martelli M.; Monaldi C.; Castagnetti F.; Gugliotta G.; Papayannidis C.; Mancini M.; Bruno S.; Venturi C.; Machova Polakova K.; Ernst T.; Maar D.; Corner A.; Cavo M.
MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis
2022 Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; Soverini S.
Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia
2022 De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S.
Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors
2022 Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B.; Rosti G.; Cavo M.; Gugliotta G.; Soverini S.
Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia
2021 Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.; Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S.
Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort?
2021 Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M.
The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities
2021 Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S.
Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis
2020 Mancini, Manuela; De Santis, Sara; Monaldi, Cecilia; Bavaro, Luana; Martelli, Margherita; Gugliotta, Gabriele; Castagnetti, Fausto; Rosti, Gianantonio; Santucci, Maria Alessandra; Martinelli, Giovanni; Cavo, Michele; Soverini, Simona
Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy
2020 Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S.
Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors
2019 Mancini M.; De Santis S.; Monaldi C.; Bavaro L.; Martelli M.; Castagnetti F.; Gugliotta G.; Rosti G.; Santucci M.A.; Martinelli G.; Cavo M.; Soverini S.
Polo-like Kinase-1 and Aurora Kinase A As Novel Therapeutic Targets in Neoplastic Mast Cells
2017 Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria Chiara Abbenante, Luana Bavaro, Margherita Martelli, Roberta Zanotti, Livio Pagano, Michele Cavo, Peter Valent, Giovanni Martinelli, Simona Soverini
SETD2 Non-Genomic Loss of Function and p53 Functional Inactivation in Advanced Systemic Mastocytosis (SM): Pathogenetic and Therapeutic Implications
2017 Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria Chiara Abbenante, Luana Bavaro, Margherita Martelli, Elisa Ficarra, Giulia Paciello, Viviana Guadagnuolo, Maria Chiara Fontana, Marco Manfrini, Roberta Zanotti, Livio Pagano, Francesco Albano, Fabio Ciceri, Chiara Elena, Patrizia Tosi, Massimo Delledonne, Peter Valent, Michele Cavo, Giovanni Martinelli, Simona Soverini
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Unstable major molecular response as a trigger for next generation sequencing-based BCR::ABL1 mutation testing in chronic myeloid leukemia | Benesova, A.; De Santis, S.; Polivkova, V.; Pecherkova, P.; Krizkova, J.; Suchankova, P.; Monaldi..., C.; Klamova, H.; Srbova, D.; Zizkova, H.; Hochhaus, A.; Soverini, S.; Machova Polakova, K. | 2024-01-01 | AMERICAN JOURNAL OF HEMATOLOGY | - | 1.01 Articolo in rivista | - |
| Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights | Iezza M.; Cortesi S.; Ottaviani E.; Mancini M.; Venturi C.; Monaldi C.; De Santis S.; Testoni N.;... Soverini S.; Rosti G.; Cavo M.; Castagnetti F. | 2023-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-12-01703-v2.pdf |
| SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted | Mancini M.; Monaldi C.; De Santis S.; Papayannidis C.; Rondoni M.; Sartor C.; Bruno S.; Pagano L....; Criscuolo M.; Zanotti R.; Bonifacio M.; Tosi P.; Arock M.; Valent P.; Cavo M.; Soverini S. | 2023-01-01 | BIOMARKER RESEARCH | - | 1.01 Articolo in rivista | Mancini_2023.pdf; 40364_2023_468_MOESM1_ESM.docx |
| CML-184 A Novel Droplet Digital PCR Strategy for Rapid and Sensitive Detection of BCR::ABL1 Kinase Domain Mutations Conferring Resistance to Second-Generation Tyrosine Kinase Inhibitors | de Santis S.; Monaldi C.; Martelli M.; Mancini M.; Bruno S.; Castagnetti F.; Gugliotta G.; Polako...va K.M.; Ernst T.; Maar D.; Corner A.; Cavo M.; Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Combined Inhibition of Polo-like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells | Mancini M.; Monaldi C.; De Santis S.; Rondoni M.; Papayannidis C.; Sartor C.; Curti A.; Bruno S.;... Cavo M.; Soverini S. | 2022-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-14-00738.pdf; cancers-14-00738-s001.zip |
| Droplet digital PCR for the detection of second-generation tyrosine kinase inhibitor-resistant BCR::ABL1 kinase domain mutations in chronic myeloid leukemia | Soverini S.; De Santis S.; Martelli M.; Monaldi C.; Castagnetti F.; Gugliotta G.; Papayannidis C....; Mancini M.; Bruno S.; Venturi C.; Machova Polakova K.; Ernst T.; Maar D.; Corner A.; Cavo M. | 2022-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| MPN-182 Droplet Digital PCR for Non-Invasive Detection of the KIT D816V Mutation in the Peripheral Blood of Patients With Suspected Systemic Mastocytosis | Monaldi C.; de Santis S.; Mancini M.; Papayannidis C.; Sartor C.; Rondoni M.; Bruno S.; Cavo M.; ...Soverini S. | 2022-01-01 | CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia | De Santis, S.; Monaldi, C.; Mancini, M.; Bruno, S.; Cavo, M.; Soverini, S. | 2022-01-01 | ONCOTARGETS AND THERAPY | - | 1.01 Articolo in rivista | OTT-289306-overcoming-resistance-to-kinase-inhibitors--the-paradigm-of-.pdf |
| Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors | Mancini M.; De Santis S.; Monaldi C.; Castagnetti F.; Lonetti A.; Bruno S.; Dan E.; Sinigaglia B....; Rosti G.; Cavo M.; Gugliotta G.; Soverini S. | 2022-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-12-901132.pdf; file supplementari.zip |
| Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia | Bruno S.; Bandini L.; Patuelli A.; Robustelli V.; Venturi C.; Mancini M.; Forte D.; De Santis S.;... Monaldi C.; Grassi A.; Chiurumbolo G.; Paolini S.; Cristiano G.; Papayannidis C.; Sartor C.; Nanni J.; Ottaviani E.; Curti A.; Cavo M.; Soverini S. | 2021-01-01 | FRONTIERS IN ONCOLOGY | - | 1.01 Articolo in rivista | fonc-11-728613.pdf |
| Targeting leukemic stem cells in chronic myeloid leukemia: Is it worth the effort? | Soverini S.; De Santis S.; Monaldi C.; Bruno S.; Mancini M. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-07093-v2.pdf |
| The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities | Bruno S.; Mancini M.; De Santis S.; Monaldi C.; Cavo M.; Soverini S. | 2021-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | ijms-22-06857-v2.pdf |
| Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis | Mancini, Manuela; De Santis, Sara; Monaldi, Cecilia; Bavaro, Luana; Martelli, Margherita; Gugliot...ta, Gabriele; Castagnetti, Fausto; Rosti, Gianantonio; Santucci, Maria Alessandra; Martinelli, Giovanni; Cavo, Michele; Soverini, Simona | 2020-01-01 | HEMATOLOGICAL ONCOLOGY | - | 1.01 Articolo in rivista | - |
| Recent advances in the molecular biology of systemic mastocytosis: Implications for diagnosis, prognosis, and therapy | Martelli M.; Monaldi C.; De Santis S.; Bruno S.; Mancini M.; Cavo M.; Soverini S. | 2020-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | Martelli_ijms_2020.pdf |
| Hyper-activation of Aurora kinase a-polo-like kinase 1-FOXM1 axis promotes chronic myeloid leukemia resistance to tyrosine kinase inhibitors | Mancini M.; De Santis S.; Monaldi C.; Bavaro L.; Martelli M.; Castagnetti F.; Gugliotta G.; Rosti... G.; Santucci M.A.; Martinelli G.; Cavo M.; Soverini S. | 2019-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Mancini_J Exp Clin Cancer Res_2019.pdf |
| Polo-like Kinase-1 and Aurora Kinase A As Novel Therapeutic Targets in Neoplastic Mast Cells | Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria C...hiara Abbenante, Luana Bavaro, Margherita Martelli, Roberta Zanotti, Livio Pagano, Michele Cavo, Peter Valent, Giovanni Martinelli, Simona Soverini | 2017-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |
| SETD2 Non-Genomic Loss of Function and p53 Functional Inactivation in Advanced Systemic Mastocytosis (SM): Pathogenetic and Therapeutic Implications | Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Maria C...hiara Abbenante, Luana Bavaro, Margherita Martelli, Elisa Ficarra, Giulia Paciello, Viviana Guadagnuolo, Maria Chiara Fontana, Marco Manfrini, Roberta Zanotti, Livio Pagano, Francesco Albano, Fabio Ciceri, Chiara Elena, Patrizia Tosi, Massimo Delledonne, Peter Valent, Michele Cavo, Giovanni Martinelli, Simona Soverini | 2017-01-01 | BLOOD | - | 1.06 Abstract in rivista | - |