BAGNOLINI, GRETA
BAGNOLINI, GRETA
FABIT - DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Assegnisti
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21
2025 Sdei, F.; Bagnolini, G.; Falchi, F.; Sosic, A.; Fabbian, S.; Duca, M.; Bolognesi, M. L.
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity
2025 Masi, Mirco; Poppi, Laura; Previtali, Viola; Nelson, Shannon R; Wynne, Kieran; Varignani, Giulia; Falchi, Federico; Veronesi, Marina; Albanesi, Ennio; Tedesco, Daniele; De Franco, Francesca; Ciamarone, Andrea; Myers, Samuel H; Ortega, Jose Antonio; Bagnolini, Greta; Ferrandi, Giovanni; Farabegoli, Fulvia; Tirelli, Nicola; Di Stefano, Giuseppina; Oliviero, Giorgio; Walsh, Naomi; Roberti, Marinella; Girotto, Stefania; Cavalli, Andrea
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
2024 Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and achieve synthetic lethality in pancreatic cancer cells
2024 Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Previtali, Viola; Roberti, Marinella; Cavalli, Andrea
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells
2024 Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Falchi, Federico; Previtali, Viola; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea
Design and synthesis of small molecules binders of pre-miRNA21 toward the regulation of oncogenic miRNA21
2024 Sdei, Federico; Bagnolini, Greta; Ghezzo, M.; Sosic, Alice; Sissi, Claudia; Bolognesi, MARIA LAURA
DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETING PRE-MIRNA21 TOWARD THE DEVELOPMENT OF RIBONUCLEASE TARGETING CHIMERAS (RIBOTACS) TO REGULATE THE ONCOGENIC MIRNA21
2024 Sdei, F.; Bagnolini, G.; Falchi, F.; Sosic, A.; Bolognesi, M. L.
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer
2024 Previtali, Viola; Masi, Mirco; Poppi, Laura; Varignani, Giulia; Falchi, Federico; Tedesco, Daniele; Wynne, Kieran; Oliviero, Giorgio; Bagnolini, Greta; Farabegoli, Fulvia; DI STEFANO, Giuseppina; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives
2024 Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs)
2024 Sdei, Federico; Bagnolini, Greta; Falchi, Federico; Ghezzo, M.; Sosic, Alice; Sissi, Claudia; Roberti, Marinella; Bolognesi, MARIA LAURA
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
2023 Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A.
Design and synthesis of RAD51-BRCA disruptors to inhibit homologous recombination and achieve synthetic lethality in cancer cells
2023 Ferrandi, Giovanni; Bagnolini, Greta; Roberti, Marinella; Cavalli, Andrea
Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA
2023 Bagnolini, G; Luu, Tb; Hargrove, Ae
Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs)
2023 Bagnolini, G.; Falchi, F.; Sdei, F.; Roberti, M.; Sosic, A.; Sissi, C.; Bolognesi, M. L.
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry
2022 Bagnolini, G.; Balboni, B.; Schipani, F.; Gioia, D.; Veronesi, M.; De Franco, F.; Kaya, C.; Jumde, R. P.; Ortega, J. A.; Girotto, S.; Hirsch, A. K. H.; Roberti, M.; Cavalli, A.
Identification of RAD51-BRCA2 inhibitors using N-acylhydrazone-based dynamic combinatorial chemistry
2022 Bagnolini, Greta; Balboni, Beatrice; Schipani, Fabrizio; Gioia, Dario; Veronesi, Marina; De Franco, Francesca; Kaya, Cansu; Jumde, Ravindra P.; Antonio Ortega, Jose; Girotto, Stefania; Hirsch, Anna K. H.; Roberti, Marinella; Cavalli, Andrea
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer
2022 Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Franco F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A.
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies
2021 Mazzei L.; Contaldo U.; Musiani F.; Cianci M.; Bagnolini G.; Roberti M.; Ciurli S.
Dihydroquinoline pyrazoline-based compound as a new RAD51-BRCA2 protein-protein disruptor to trigger synthetic lethality in pancreatic cancer
2020 Bagnolini, Greta; Manerba, Marcella; Balboni, Andrea; Antonio Ortega, Jose; Gioia, Dario; De Franco, Francesca; Roberti, Marinella; Cavalli, Andrea
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib
2020 Bagnolini G.; Milano D.; Manerba M.; Schipani F.; Ortega J.A.; Gioia D.; Falchi F.; Balboni A.; Farabegoli F.; De Franco F.; Robertson J.; Pellicciari R.; Pallavicini I.; Peri S.; Minucci S.; Girotto S.; Di Stefano G.; Roberti M.; Cavalli A.