IOAN, PIERFRANCO
IOAN, PIERFRANCO
AFORM - AREA FORMAZIONE E DOTTORATO
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism
2016 Carosati, Emanuele; Cosimelli, Barbara; Ioan, Pierfranco; Severi, Elda; Katneni, Kasiram; Chiu, Francis C. K.; Saponara, Simona; Fusi, Fabio; Frosini, Maria; Matucci, Rosanna; Micucci, Matteo; Chiarini, Alberto; Spinelli, Domenico; Budriesi, Roberta
Synthesis and L-type calcium channel blocking activity of new chiral oxadiazolothiazinones
2015 Carosati, E.; Ioan, P.; Barrano, G.B.; Caccamese, S.; Cosimelli, B.; Devlin, F.J.; Severi, E.; Spinelli, D.; Superchi, S.; Budriesi, R.
Castanea sativa Mill. Extract contracts gallbladder and relaxes sphincter of oddi in Guinea Pig: A natural approach to biliary tract motility disorders
2014 Micucci, M.; Ioan, P.; Aldini, R.; Cevenini, M.; Alvisi, V.; Ruffilli, C.; Chiarini, A.; Budriesi, R.
Playing with opening and closing of heterocycles: Using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors
2014 Spinelli, D.; Budriesi, R.; Cosimelli, B.; Severi, E.; Micucci, M.; Baroni, M.; Fusi, F.; Ioan, P.; Cross, S.; Frosini, M.; Saponara, S.; Matucci, R.; Rosano, C.; Viale, M.; Chiarini, A.; Carosati, E.
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity
2013 Alessandra Locatelli;Sandro Cosconati;Matteo Micucci;Alberto Leoni;Luciana Marinelli;Andrea Bedini;Pierfranco Ioan;Santi Mario Spampinato;Ettore Novellino;Alberto Chiarini;Roberta Budriesi
Sweet chestnut (Castanea Sativa Mill.) bark extract: cardiovascular activity and myocyte protection against oxidative damage
2013 A. Chiarini; M. Micucci; M. Malaguti; R. Budriesi; P. Ioan; M. Lenzi; C. Fimognari; T. Gallina Toschi; P. Comandini; S. Hrelia
1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets
2012 E Carosati; P Ioan; M Micucci; F Broccatelli; G Cruciani; BS Zhorov; A Chiarini; R Budriesi
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects
2012 Pierfranco Ioan; Alessia Ciogli; Francesco Sirci; Roberta Budriesi; Barbara Cosimelli; Marco Pierini; Elda Severi; Alberto Chiarini; Gabriele Cruciani; Francesco Gasparrini; Domenico Spinelli; Emanuele Carosati
Castanea sativa mill. Extract: a Co Adjuvant in the Treatment of Colestasis.
2012 Micucci M; Ioan P; Arroo R; Ruparelia K; Chiarini A; Budriesi R
Curcuma longa Extract Exerts a Myorelaxant Effect on the Ileum and Colon in a Mouse Experimental Colitis Model, Independent of the Anti-Inflammatory Effect
2012 Aldini R; Budriesi R; Roda G; Micucci M; Ioan P; D’Errico-Grigioni A; Sartini A; Guidetti E; Marocchi M; Cevenini M; Rosini F; Montagnani M; Chiarini A; Mazzella G
Effects of natural extract of chestnut wood in guinea pig ileum and proximal colon.
2012 Micucci M; Budriesi R; Ioan P; Chiarini A; Giorgini S
1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives. (Part 1): Action in Ion Channels and GPCRs.
2011 Ioan P; Carosati E; Micucci M;Cruciani G; Broccatelli F; ZhorovBS; Chiarini A ; Budriesi R
Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines.
2011 R. Budriesi; P. Ioan; A. Leoni; N. Pedemonte; A. Locatelli; M. Micucci; A. Chiarini; L. J. Galietta.
Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis
2011 M. Viale; C. Cordazzo; D. de Totero; R. Budriesi; C. Rosano; A. Leoni; P. Ioan; C. Aiello; M. Croce; A. Andreani; M. Rambaldi; P. Russo; A. Chiarini; D. Spinelli
Preliminary Finding on a New Calcium Channel Entry Blocker Chemotype: 5,6-Diamino-4-hydroxy-2-mercaptopyrimidine Derivatives.
2011 Cosimelli B; Severi E; Novellino E; Cavaccini A; Cataldi M; Budriesi R; Micucci M; Chiarini A; Ioan P
Studio in vitro ed ex vivo dell’ estratto di corteccia di Castanea sativa Mill: azione citoprotettiva e cardiomodulatrice.
2011 Micucci M; Ioan P; Malaguti M; Budriesi R; Fimognari C; Lenzi M; Hrelia S; Chiarini A
Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation.
2010 B. Tasso; R. Budriesi; I. Vazzana; P. Ioan; M. Micucci; F. Novelli; M. Tonelli; A. Sparatore; A. Chiarini; F. Sparatore
Quinolizidine derivatives as antiarrhytmic agents.
2010 B. Tasso; R. Budriesi; I. Vazzana; P. Ioan; M. Micucci; F. Novelli; M. Tonelli; A. Sparatore; A. Chiarini; F. Sparatore
Stop Fitan: Antispasmodic Effect of Natural Extract of Chestnut Wood in Guinea Pig Ileum and Proximal Colon Smooth Muscle
2010 R. Budriesi ; P. Ioan; M. Micucci; E. Micucci; V. Limongelli; A. Chiarini
Tannini idrosolubili con attività gastro-entero protettiva
2010 R. Budriesi; M. Micucci; P. Ioan; A. Chiarini;
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism | Carosati, Emanuele; Cosimelli, Barbara; Ioan, Pierfranco; Severi, Elda; Katneni, Kasiram; Chiu, F...rancis C. K.; Saponara, Simona; Fusi, Fabio; Frosini, Maria; Matucci, Rosanna; Micucci, Matteo; Chiarini, Alberto; Spinelli, Domenico; Budriesi, Roberta | 2016-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Synthesis and L-type calcium channel blocking activity of new chiral oxadiazolothiazinones | Carosati, E.; Ioan, P.; Barrano, G.B.; Caccamese, S.; Cosimelli, B.; Devlin, F.J.; Severi, E.; Sp...inelli, D.; Superchi, S.; Budriesi, R. | 2015-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Castanea sativa Mill. Extract contracts gallbladder and relaxes sphincter of oddi in Guinea Pig: A natural approach to biliary tract motility disorders | Micucci, M.; Ioan, P.; Aldini, R.; Cevenini, M.; Alvisi, V.; Ruffilli, C.; Chiarini, A.; Budriesi..., R. | 2014-01-01 | JOURNAL OF MEDICINAL FOOD | - | 1.01 Articolo in rivista | - |
| Playing with opening and closing of heterocycles: Using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors | Spinelli, D.; Budriesi, R.; Cosimelli, B.; Severi, E.; Micucci, M.; Baroni, M.; Fusi, F.; Ioan, P....; Cross, S.; Frosini, M.; Saponara, S.; Matucci, R.; Rosano, C.; Viale, M.; Chiarini, A.; Carosati, E. | 2014-01-01 | MOLECULES | - | 1.01 Articolo in rivista | - |
| Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity | Alessandra Locatelli;Sandro Cosconati;Matteo Micucci;Alberto Leoni;Luciana Marinelli;Andrea Bedin...i;Pierfranco Ioan;Santi Mario Spampinato;Ettore Novellino;Alberto Chiarini;Roberta Budriesi | 2013-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Sweet chestnut (Castanea Sativa Mill.) bark extract: cardiovascular activity and myocyte protection against oxidative damage | A. Chiarini; M. Micucci; M. Malaguti; R. Budriesi; P. Ioan; M. Lenzi; C. Fimognari; T. Gallina To...schi; P. Comandini; S. Hrelia | 2013-01-01 | OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | - | 1.01 Articolo in rivista | Oxidative Medicine and Cellular Longevity 2013.pdf; 471790.pdf |
| 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets | E Carosati; P Ioan; M Micucci; F Broccatelli; G Cruciani; BS Zhorov; A Chiarini; R Budriesi | 2012-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects | Pierfranco Ioan; Alessia Ciogli; Francesco Sirci; Roberta Budriesi; Barbara Cosimelli; Marco Pier...ini; Elda Severi; Alberto Chiarini; Gabriele Cruciani; Francesco Gasparrini; Domenico Spinelli; Emanuele Carosati | 2012-01-01 | ORGANIC & BIOMOLECULAR CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Castanea sativa mill. Extract: a Co Adjuvant in the Treatment of Colestasis. | Micucci M; Ioan P; Arroo R; Ruparelia K; Chiarini A; Budriesi R | 2012-01-01 | - | s.n. | 4.02 Riassunto (Abstract) | - |
| Curcuma longa Extract Exerts a Myorelaxant Effect on the Ileum and Colon in a Mouse Experimental Colitis Model, Independent of the Anti-Inflammatory Effect | Aldini R; Budriesi R; Roda G; Micucci M; Ioan P; D’Errico-Grigioni A; Sartini A; Guidetti E; Maro...cchi M; Cevenini M; Rosini F; Montagnani M; Chiarini A; Mazzella G | 2012-01-01 | PLOS ONE | - | 1.01 Articolo in rivista | journal.pone.0044650.PDF |
| Effects of natural extract of chestnut wood in guinea pig ileum and proximal colon. | Micucci M; Budriesi R; Ioan P; Chiarini A; Giorgini S | 2012-01-01 | - | s.n. | 4.02 Riassunto (Abstract) | - |
| 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives. (Part 1): Action in Ion Channels and GPCRs. | Ioan P; Carosati E; Micucci M;Cruciani G; Broccatelli F; ZhorovBS; Chiarini A ; Budriesi R | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines. | R. Budriesi; P. Ioan; A. Leoni; N. Pedemonte; A. Locatelli; M. Micucci; A. Chiarini; L. J. Galietta. | 2011-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis | M. Viale; C. Cordazzo; D. de Totero; R. Budriesi; C. Rosano; A. Leoni; P. Ioan; C. Aiello; M. Cro...ce; A. Andreani; M. Rambaldi; P. Russo; A. Chiarini; D. Spinelli | 2011-01-01 | INVESTIGATIONAL NEW DRUGS | - | 1.01 Articolo in rivista | - |
| Preliminary Finding on a New Calcium Channel Entry Blocker Chemotype: 5,6-Diamino-4-hydroxy-2-mercaptopyrimidine Derivatives. | Cosimelli B; Severi E; Novellino E; Cavaccini A; Cataldi M; Budriesi R; Micucci M; Chiarini A; Io...an P | 2011-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Studio in vitro ed ex vivo dell’ estratto di corteccia di Castanea sativa Mill: azione citoprotettiva e cardiomodulatrice. | Micucci M; Ioan P; Malaguti M; Budriesi R; Fimognari C; Lenzi M; Hrelia S; Chiarini A | 2011-01-01 | - | s.n. | 4.02 Riassunto (Abstract) | - |
| Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation. | B. Tasso; R. Budriesi; I. Vazzana; P. Ioan; M. Micucci; F. Novelli; M. Tonelli; A. Sparatore; A. ...Chiarini; F. Sparatore | 2010-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Quinolizidine derivatives as antiarrhytmic agents. | B. Tasso; R. Budriesi; I. Vazzana; P. Ioan; M. Micucci; F. Novelli; M. Tonelli; A. Sparatore; A. ...Chiarini; F. Sparatore | 2010-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Stop Fitan: Antispasmodic Effect of Natural Extract of Chestnut Wood in Guinea Pig Ileum and Proximal Colon Smooth Muscle | R. Budriesi ; P. Ioan; M. Micucci; E. Micucci; V. Limongelli; A. Chiarini | 2010-01-01 | JOURNAL OF MEDICINAL FOOD | - | 1.01 Articolo in rivista | - |
| Tannini idrosolubili con attività gastro-entero protettiva | R. Budriesi; M. Micucci; P. Ioan; A. Chiarini; | 2010-01-01 | NATURAL 1 | - | 4.02 Riassunto (Abstract) | - |