MARTELLI, ALBERTO MARIA
MARTELLI, ALBERTO MARIA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Docenti di ruolo di Ia fascia
Alberto Maria Martelli.; A.M. Martelli.; Alberto M. Martelli; MARTELLI A.; MARTELLI AM.
Effects of chloroquine and hydroxychloroquine on the sensitivity of pancreatic cancer cells to targeted therapies
2023 McCubrey, James A; Abrams, Stephen L; Follo, Matilde Y; Manzoli, Lucia; Ratti, Stefano; Martelli, Alberto M; Cervello, Melchiorre
Understanding the Roles of the Hedgehog Signaling Pathway during T-Cell Lymphopoiesis and in T-Cell Acute Lymphoblastic Leukemia (T-ALL)
2023 Martelli, Alberto M; Paganelli, Francesca; Truocchio, Serena; Palumbo, Carla; Chiarini, Francesca; McCubrey, James A
Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53
2022 Abrams, S. L.; Akula, S. M.; Steelman, L. S.; Follo, M. Y.; Cocco, L.; Ratti, S.; Martelli, A. M.; Libra, M.; Falzone, L.; Candido, S.; Montalto, G.; Cervello, M.; Lombardi, P.; Mccubrey, J. A.
Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53
2022 Abrams S.L.; Duda P.; Akula S.M.; Steelman L.S.; Follo M.Y.; Cocco L.; Ratti S.; Martelli A.M.; Montalto G.; Emma M.R.; Cervello M.; Rakus D.; Gizak A.; McCubrey J.A.
Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression
2022 McCubrey, James A; Yang, Li V; Abrams, Stephen L; Steelman, Linda S; Follo, Matilde Y; Cocco, Lucio; Ratti, Stefano; Martelli, Alberto M; Augello, Giuseppa; Cervello, Melchiorre
Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
2022 Chiarini, Francesca; Paganelli, Francesca; Balestra, Tommaso; Capanni, Cristina; Fazio, Antonietta; Manara, Maria Cristina; Landuzzi, Lorena; Petrini, Stefania; Evangelisti, Camilla; Lollini, Pier-Luigi; Martelli, Alberto M.; Lattanzi, Giovanna; Scotlandi, Katia
Pathobiology and therapeutic relevance of GSK-3 in chronic hematological malignancies.
2022 A.M. Martelli, F. Paganelli, C. Evangelisti, F. Chiarini, J.A. McCubrey.
The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma
2022 Lampis S.; Raieli S.; Montemurro L.; Bartolucci D.; Amadesi C.; Bortolotti S.; Angelucci S.; Scardovi A.L.; Nieddu G.; Cerisoli L.; Paganelli F.; Valente S.; Fischer M.; Martelli A.M.; Pasquinelli G.; Pession A.; Hrelia P.; Tonelli R.
GSK-3: a multifaceted player in acute leukemias.
2021 A.M. Martelli, C. Evangelisti, F. Paganelli, F. Chiarini, J.A. McCubrey.
GSK-3β can regulate the sensitivity of pancreatic cells to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.
2021 S.L. Abrams, S.M. Akula, A.K Meher, L. S. Steelman, A. Gizak, P. Duda, D. Rakus, A.M. Martelli, S. Ratti, L. Cocco, G. Montalto, M. Cervello, P. Ruvolo, M. Libra, L. Falzone, S. Candido, J.A. McCubrey.
Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners.
2021 T. Tanaka, T. Nakano, Y. Hozumi, A.M. Martelli, K. Goto.
Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53
2021 S.L. Abrams, S.M. Akula, A.M. Martelli, L. Cocco, S. Ratti, M. Libra, S. Candido, G.Montalto, M. Cervello, A. Gizak, D. Rakus, L.S. Steelman, J.A. McCubrey.
The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine
2021 Paganelli, Francesca; Chiarini, Francesca; Palmieri, Annalisa; Martinelli, Marcella; Sena, Paola; Bertacchini, Jessika; Roncucci, Luca; Cappellini, Alessandra; Martelli, Alberto M; Bonucci, Massimo; Fiorentini, Carla; Hammarberg Ferri, Ivano
Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells
2020 Akula S.M.; Candido S.; Abrams S.L.; Steelman L.S.; Lertpiriyapong K.; Cocco L.; Ramazzotti G.; Ratti S.; Follo M.Y.; Martelli A.M.; Murata R.M.; Rosalen P.L.; Bueno-Silva B.; Matias de Alencar S.; Falasca M.; Montalto G.; Cervello M.; Notarbartolo M.; Gizak A.; Rakus D.; Libra M.; McCubrey J.A.
B-all complexity: Is targeted therapy still a valuable approach for pediatric patients?
2020 Ratti S.; Lonetti A.; Follo M.Y.; Paganelli F.; Martelli A.M.; Chiarini F.; Evangelisti C.
Cancer therapy and treatments during COVID-19 era
2020 Akula S.M.; Abrams S.L.; Steelman L.S.; Candido S.; Libra M.; Lerpiriyapong K.; Cocco L.; Ramazzotti G.; Ratti S.; Follo M.Y.; Martelli A.M.; Blalock W.L.; Piazzi M.; Montalto G.; Cervello M.; Notarbartolo M.; Basecke J.; McCubrey J.A.
Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer.
2020 C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli.
Deregulated PTEN/PI3K/AKT/mTOR signaling in prostate cancer: still a potential druggable target?
2020 L. Braglia, M. Zavatti, M. Vinceti, A.M. Martelli, S. Marmiroli.
Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines
2020 Chappell, William H; Candido, Saverio; Abrams, Stephen L; Akula, Shaw M; Steelman, Linda S; Martelli, Alberto M; Ratti, Stefano; Cocco, Lucio; Cervello, Melchiorre; Montalto, Giuseppe; Nicoletti, Ferdinando; Libra, Massimo; McCubrey, James A
Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml
2020 Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Martelli A.M.; Locatelli F.; Pession A.; Masetti R.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Effects of chloroquine and hydroxychloroquine on the sensitivity of pancreatic cancer cells to targeted therapies | McCubrey, James A; Abrams, Stephen L; Follo, Matilde Y; Manzoli, Lucia; Ratti, Stefano; Martelli,... Alberto M; Cervello, Melchiorre | 2023-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | Effects of chloroquine and hydroxychloroquine on the sensitivity of pancreatic cancer cells to targeted therapies.pdf |
| Understanding the Roles of the Hedgehog Signaling Pathway during T-Cell Lymphopoiesis and in T-Cell Acute Lymphoblastic Leukemia (T-ALL) | Martelli, Alberto M; Paganelli, Francesca; Truocchio, Serena; Palumbo, Carla; Chiarini, Francesca...; McCubrey, James A | 2023-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - | 1.01 Articolo in rivista | IntJMolSci-2023-HedgeHog.pdf |
| Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53 | Abrams, S. L.; Akula, S. M.; Steelman, L. S.; Follo, M. Y.; Cocco, L.; Ratti, S.; Martelli, A. M....; Libra, M.; Falzone, L.; Candido, S.; Montalto, G.; Cervello, M.; Lombardi, P.; Mccubrey, J. A. | 2022-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | Effects of the MDM2 inhibitor_postprint.pdf |
| Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53 | Abrams S.L.; Duda P.; Akula S.M.; Steelman L.S.; Follo M.Y.; Cocco L.; Ratti S.; Martelli A.M.; M...ontalto G.; Emma M.R.; Cervello M.; Rakus D.; Gizak A.; McCubrey J.A. | 2022-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-11-00794.pdf |
| Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression | McCubrey, James A; Yang, Li V; Abrams, Stephen L; Steelman, Linda S; Follo, Matilde Y; Cocco, Luc...io; Ratti, Stefano; Martelli, Alberto M; Augello, Giuseppa; Cervello, Melchiorre | 2022-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-11-02155-v2.pdf |
| Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma | Chiarini, Francesca; Paganelli, Francesca; Balestra, Tommaso; Capanni, Cristina; Fazio, Antoniett...a; Manara, Maria Cristina; Landuzzi, Lorena; Petrini, Stefania; Evangelisti, Camilla; Lollini, Pier-Luigi; Martelli, Alberto M.; Lattanzi, Giovanna; Scotlandi, Katia | 2022-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | Lamin Cell Death Dis.pdf; 41419_2022_4729_MOESM1_ESM.pdf |
| Pathobiology and therapeutic relevance of GSK-3 in chronic hematological malignancies. | A.M. Martelli, F. Paganelli, C. Evangelisti, F. Chiarini, J.A. McCubrey. | 2022-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-11-01812-v3 (1).pdf |
| The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma | Lampis S.; Raieli S.; Montemurro L.; Bartolucci D.; Amadesi C.; Bortolotti S.; Angelucci S.; Scar...dovi A.L.; Nieddu G.; Cerisoli L.; Paganelli F.; Valente S.; Fischer M.; Martelli A.M.; Pasquinelli G.; Pession A.; Hrelia P.; Tonelli R. | 2022-01-01 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | - | 1.01 Articolo in rivista | Lampis_et_al-2022-Journal_of_Experimental_&_Clinical_Cancer_Research.pdf; 19688410.zip |
| GSK-3: a multifaceted player in acute leukemias. | A.M. Martelli, C. Evangelisti, F. Paganelli, F. Chiarini, J.A. McCubrey. | 2021-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | GSK-3 a multifaceted player in acute leukemias_postprint.pdf |
| GSK-3β can regulate the sensitivity of pancreatic cells to chemotherapeutic drugs, targeted therapeutics and nutraceuticals. | S.L. Abrams, S.M. Akula, A.K Meher, L. S. Steelman, A. Gizak, P. Duda, D. Rakus, A.M. Martelli, S.... Ratti, L. Cocco, G. Montalto, M. Cervello, P. Ruvolo, M. Libra, L. Falzone, S. Candido, J.A. McCubrey. | 2021-01-01 | CELLS | - | 1.01 Articolo in rivista | cells-10-00816.pdf |
| Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners. | T. Tanaka, T. Nakano, Y. Hozumi, A.M. Martelli, K. Goto. | 2021-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53 | S.L. Abrams, S.M. Akula, A.M. Martelli, L. Cocco, S. Ratti, M. Libra, S. Candido, G.Montalto, M. ...Cervello, A. Gizak, D. Rakus, L.S. Steelman, J.A. McCubrey. | 2021-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | - |
| The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine | Paganelli, Francesca; Chiarini, Francesca; Palmieri, Annalisa; Martinelli, Marcella; Sena, Paola;... Bertacchini, Jessika; Roncucci, Luca; Cappellini, Alessandra; Martelli, Alberto M; Bonucci, Massimo; Fiorentini, Carla; Hammarberg Ferri, Ivano | 2021-01-01 | PHARMACEUTICALS | - | 1.01 Articolo in rivista | Paganelli 2021 Combination of AHCC and ETAS in CRC.pdf; pharmaceuticals-14-01325-s001.zip |
| Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells | Akula S.M.; Candido S.; Abrams S.L.; Steelman L.S.; Lertpiriyapong K.; Cocco L.; Ramazzotti G.; R...atti S.; Follo M.Y.; Martelli A.M.; Murata R.M.; Rosalen P.L.; Bueno-Silva B.; Matias de Alencar S.; Falasca M.; Montalto G.; Cervello M.; Notarbartolo M.; Gizak A.; Rakus D.; Libra M.; McCubrey J.A. | 2020-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | - |
| B-all complexity: Is targeted therapy still a valuable approach for pediatric patients? | Ratti S.; Lonetti A.; Follo M.Y.; Paganelli F.; Martelli A.M.; Chiarini F.; Evangelisti C. | 2020-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-12-03498-v3(1).pdf |
| Cancer therapy and treatments during COVID-19 era | Akula S.M.; Abrams S.L.; Steelman L.S.; Candido S.; Libra M.; Lerpiriyapong K.; Cocco L.; Ramazzo...tti G.; Ratti S.; Follo M.Y.; Martelli A.M.; Blalock W.L.; Piazzi M.; Montalto G.; Cervello M.; Notarbartolo M.; Basecke J.; McCubrey J.A. | 2020-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | Cancer Therapy and Treatments_postprint.pdf |
| Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer. | C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli. | 2020-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| Deregulated PTEN/PI3K/AKT/mTOR signaling in prostate cancer: still a potential druggable target? | L. Braglia, M. Zavatti, M. Vinceti, A.M. Martelli, S. Marmiroli. | 2020-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines | Chappell, William H; Candido, Saverio; Abrams, Stephen L; Akula, Shaw M; Steelman, Linda S; Marte...lli, Alberto M; Ratti, Stefano; Cocco, Lucio; Cervello, Melchiorre; Montalto, Giuseppe; Nicoletti, Ferdinando; Libra, Massimo; McCubrey, James A | 2020-01-01 | AGING | - | 1.01 Articolo in rivista | aging-v12i11-103377.pdf |
| Inhibition of methyltransferase dot1l sensitizes to sorafenib treatment aml cells irrespective of mll-rearrangements: A novel therapeutic strategy for pediatric aml | Lonetti A.; Indio V.; Laginestra M.A.; Tarantino G.; Chiarini F.; Astolfi A.; Bertuccio S.N.; Mar...telli A.M.; Locatelli F.; Pession A.; Masetti R. | 2020-01-01 | CANCERS | - | 1.01 Articolo in rivista | cancers-12-01972.pdf; cancers-12-01972-s001.zip |