MARTELLI, ALBERTO MARIA
MARTELLI, ALBERTO MARIA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Docenti di ruolo di Ia fascia
Alberto Maria Martelli.; A.M. Martelli.; Alberto M. Martelli; MARTELLI A.; MARTELLI AM.
A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia.
2012-01-01 F. Chiarini; A. Lonetti; G. Teti; E. Orsini; D. Bressanin; A.Cappellini; F. Ricci; P. L. Tazzari; A. Ognibene; M. Falconi; P. Pagliaro; I. Iacobucci; G. Martinelli; S. Amadori; J.A. McCubrey; A.M. Martelli.
Aberrant Proliferative and Apoptotic Pathways in Acute Lymphoblastic Leukemia (ALL):Molecular Therapies to Overcome Chemo-Resistance.
2011-01-01 A. Tafuri; M. Milella; S. Iacovelli; F. De Cave;C. Gregorj; P. Bergamo; A.Miele; R.Licchetta;M. Konopleva; J.A. McCubrey; A.M. Martelli; R. Foà; M.T Petrucci; M.R. Ricciardi.
Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells.
2019-01-01 Abrams SL, Follo MY, Steelman LS, Lertpiriyapong K, Cocco L, Ratti S, Martelli AM, Candido S, Libra M, Murata RM, Rosalen PL, Montalto G, Cervello M, Gizak A, Rakus D, Mao W, Lombardi P, McCubrey JA.
Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells.
2019-01-01 S.M. Akula, S. Candido, M. Libra, S.L. Abrams, L.S. Steelman, K. Lertpiriyapong, G. Ramazzotti, S. Ratti, M.Y. Follo, A.M. Martelli, R.M. Murata, P.L. Rosalen, B. Bueno-Silva, S. Matias de Alencar, G. Montalto, M. Cervello, A. Gizak, D. Rakus, W. Mao, H.-L. Lin, P. Lombardi, J.A. McCubrey.
Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells
2020-01-01 Akula S.M.; Candido S.; Abrams S.L.; Steelman L.S.; Lertpiriyapong K.; Cocco L.; Ramazzotti G.; Ratti S.; Follo M.Y.; Martelli A.M.; Murata R.M.; Rosalen P.L.; Bueno-Silva B.; Matias de Alencar S.; Falasca M.; Montalto G.; Cervello M.; Notarbartolo M.; Gizak A.; Rakus D.; Libra M.; McCubrey J.A.
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients
2012-01-01 Follo M.Y.; Mongiorgi S.; Clissa C.; Paolini S.; Martinelli G.; Martelli A.M.; Fioravanti G.; Manzoli L.; Finelli C.; Cocco L.
Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235, against T-cell acute lymphoblastic leukemia.
2010-01-01 F. Chiarini; C. Grimaldi; F. Ricci; P. L. Tazzari; C.Evangelisti; A. Ognibene; M.Battistelli; E. Falcieri; F. Melchionda; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli.
Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation.
2014-01-01 C Simioni; A Cani; A.M. Martelli; G. Zauli; G. Tabellini; J.A. McCubrey; S. Capitani; L.M. Neri .
Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia
2014-01-01 A. Lonetti; I. Lopes Antunes; F. Chiarini; E. Orsini; F. Buontempo; F. Ricci; P.L. Tazzari; P. Pagliaro; F. Melchionda; A. Pession; A. Bertaina; F. Locatelli; J.A. McCubrey; J.T. Barata; A.M. Martelli.
Activity of the Selective IκB kinase Inhibitor BMS-345541 against T-Cell Acute Lymphoblastic Leukemia: involvement of FOXO3a
2012-01-01 F. Buontempo; F. Chiarini; D. Bressanin; G. Tabellini; F. Melchionda; A. Pession; M. Fini; L.M. Neri; J.A. McCubrey; A.M. Martelli
Advances in Targeting Signal Transduction Pathways.
2012-01-01 J.A. McCubrey; L.S. Steelman; W.H. Chappell; L. Sun; N.M. Davis; S.L. Abrams; R.A. Franklin; L. Cocco; C. Evangelisti; F. Chiarini; A.M. Martelli; M. Libra; S. Candido; G. Ligresti; G. Malaponte; M.C. Mazzarino; P. Fagone; M. Donia; F. Nicoletti; J. Polesel; R. Talamini; J. Bäsecke; S. Mijatovic; D. Maksimovic-Ivanic; M. Milella; A. Tafuri; J. Dulińska-Litewka; P. Laidler; A. B. D’Assoro; L. Drobot ; K. Umezawa; G. Montalto; M. Cervello; Z. N. Demidenko.
Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: from biology to therapeutic targeting.
2016-01-01 Chiarini, F; Lonetti, A; Evangelisti, C; Buontempo, F; Orsini, E; Evangelisti, C; Cappellini, A; Neri, LM; McCubrey, Ja; Martelli, AM.
Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells.
2019-01-01 F. Charini, C. Evangelisti, G. Lattanzi, J.A. McCubrey, A.M. Martelli.
The Akt inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated Akt-1 and synergizes with conventional chemotherapy
2013-01-01 C. Simioni; A.M. Martelli; A. Cani; R. Cetin-Atalay; J.A. McCubrey; S. Capitani; L.M. Neri.
Akt is a therapeutic target in cancer
2008-01-01 Steelman L.S.; Stadelman K.M.; Chappell W.H.; Horn S.; Basecke J.; Cervello M.; Nicoletti F.; Libra M.; Stivala F.; Martelli A.M.; McCubrey J.A.
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy
2008-01-01 McCubrey J.A.; Sokolosky M.L.; Lehmann B.D.; Taylor J.R.; Navolanic P.M.; Chappell W.H.; Abrams S.L.; Stadelman K.M.; Wong E.W.; Misaghian N.; Horn S.; Bäsecke J.; Libra M.; Stivala F.; Ligresti G.; Tafuri A.; Milella M.; Zarzycki M.; Dzugaj A.; Chiarini F.; Evangelisti C.; Martelli A.M.; Terrian D.M.; Franklin R.A.; Steelman L.S.
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications.
2012-01-01 Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bortul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M.
Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation
2005-01-01 A. Cappellini; P.L. Tazzari; I. Mantovani; A.M. Billi; C. Tassi; F. Ricci; R. Conte; A.M. Martelli
Antioxidants in the prevention of UVB-induced keratynocyte apoptosis.
2014-01-01 S. Salucci; S. Burattini; D. Curzi; F. Buontempo; A.M. Martelli; G. Zappia; E. Falcieri; M. Battistelli.
Application of flow cytometry to molecular medicine: Detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts
2005-01-01 Cappellini A; Mantovani I; Tazzari PL; Grafone T; Martinelli G; Cocco L; Martelli AM
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia. | F. Chiarini; A. Lonetti; G. Teti; E. Orsini; D. Bressanin; A.Cappellini; F. Ricci; P. L. Tazzari;... A. Ognibene; M. Falconi; P. Pagliaro; I. Iacobucci; G. Martinelli; S. Amadori; J.A. McCubrey; A.M. Martelli. | 2012-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Aberrant Proliferative and Apoptotic Pathways in Acute Lymphoblastic Leukemia (ALL):Molecular Therapies to Overcome Chemo-Resistance. |
A. Tafuri; M. Milella; S. Iacovelli; F. De Cave;C. Gregorj; P. Bergamo; A.Miele; R.Licchetta;M. K...onopleva; J.A. McCubrey; A.M. Martelli; R. Foà; M.T Petrucci; M.R. Ricciardi. |
2011-01-01 | - | InTech | 2.01 Capitolo / saggio in libro | - |
| Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells. | Abrams SL, Follo MY, Steelman LS, Lertpiriyapong K, Cocco L, Ratti S, Martelli AM, Candido S, Lib...ra M, Murata RM, Rosalen PL, Montalto G, Cervello M, Gizak A, Rakus D, Mao W, Lombardi P, McCubrey JA. | 2019-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | - |
| Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells. | S.M. Akula, S. Candido, M. Libra, S.L. Abrams, L.S. Steelman, K. Lertpiriyapong, G. Ramazzotti, S.... Ratti, M.Y. Follo, A.M. Martelli, R.M. Murata, P.L. Rosalen, B. Bueno-Silva, S. Matias de Alencar, G. Montalto, M. Cervello, A. Gizak, D. Rakus, W. Mao, H.-L. Lin, P. Lombardi, J.A. McCubrey. | 2019-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | - |
| Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells | Akula S.M.; Candido S.; Abrams S.L.; Steelman L.S.; Lertpiriyapong K.; Cocco L.; Ramazzotti G.; R...atti S.; Follo M.Y.; Martelli A.M.; Murata R.M.; Rosalen P.L.; Bueno-Silva B.; Matias de Alencar S.; Falasca M.; Montalto G.; Cervello M.; Notarbartolo M.; Gizak A.; Rakus D.; Libra M.; McCubrey J.A. | 2020-01-01 | ADVANCES IN BIOLOGICAL REGULATION | - | 1.01 Articolo in rivista | - |
| Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients | Follo M.Y.; Mongiorgi S.; Clissa C.; Paolini S.; Martinelli G.; Martelli A.M.; Fioravanti G.; Man...zoli L.; Finelli C.; Cocco L. | 2012-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235, against T-cell acute lymphoblastic leukemia. | F. Chiarini; C. Grimaldi; F. Ricci; P. L. Tazzari; C.Evangelisti; A. Ognibene; M.Battistelli; E. ...Falcieri; F. Melchionda; A. Pession; P. Pagliaro; J.A. McCubrey; A.M. Martelli. | 2010-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation. | C Simioni; A Cani; A.M. Martelli; G. Zauli; G. Tabellini; J.A. McCubrey; S. Capitani; L.M. Neri . | 2014-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia | A. Lonetti; I. Lopes Antunes; F. Chiarini; E. Orsini; F. Buontempo; F. Ricci; P.L. Tazzari; P. Pa...gliaro; F. Melchionda; A. Pession; A. Bertaina; F. Locatelli; J.A. McCubrey; J.T. Barata; A.M. Martelli. | 2014-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Activity of the Selective IκB kinase Inhibitor BMS-345541 against T-Cell Acute Lymphoblastic Leukemia: involvement of FOXO3a | F. Buontempo; F. Chiarini; D. Bressanin; G. Tabellini; F. Melchionda; A. Pession; M. Fini; L.M. N...eri; J.A. McCubrey; A.M. Martelli | 2012-01-01 | CELL CYCLE | - | 1.01 Articolo in rivista | - |
| Advances in Targeting Signal Transduction Pathways. | J.A. McCubrey; L.S. Steelman; W.H. Chappell; L. Sun; N.M. Davis; S.L. Abrams; R.A. Franklin; L. C...occo; C. Evangelisti; F. Chiarini; A.M. Martelli; M. Libra; S. Candido; G. Ligresti; G. Malaponte; M.C. Mazzarino; P. Fagone; M. Donia; F. Nicoletti; J. Polesel; R. Talamini; J. Bäsecke; S. Mijatovic; D. Maksimovic-Ivanic; M. Milella; A. Tafuri; J. Dulińska-Litewka; P. Laidler; A. B. D’Assoro; L. Drobot ; K. Umezawa; G. Montalto; M. Cervello; Z. N. Demidenko. | 2012-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: from biology to therapeutic targeting. | Chiarini, F; Lonetti, A; Evangelisti, C; Buontempo, F; Orsini, E; Evangelisti, C; Cappellini, A; ...Neri, LM; McCubrey, Ja; Martelli, AM. | 2016-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells. | F. Charini, C. Evangelisti, G. Lattanzi, J.A. McCubrey, A.M. Martelli. | 2019-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | - | 1.01 Articolo in rivista | - |
| The Akt inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated Akt-1 and synergizes with conventional chemotherapy | C. Simioni; A.M. Martelli; A. Cani; R. Cetin-Atalay; J.A. McCubrey; S. Capitani; L.M. Neri. | 2013-01-01 | ONCOTARGET | - | 1.01 Articolo in rivista | - |
| Akt is a therapeutic target in cancer | Steelman L.S.; Stadelman K.M.; Chappell W.H.; Horn S.; Basecke J.; Cervello M.; Nicoletti F.; Lib...ra M.; Stivala F.; Martelli A.M.; McCubrey J.A. | 2008-01-01 | EXPERT OPINION ON THERAPEUTIC TARGETS | - | 1.01 Articolo in rivista | - |
| Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy | McCubrey J.A.; Sokolosky M.L.; Lehmann B.D.; Taylor J.R.; Navolanic P.M.; Chappell W.H.; Abrams S....L.; Stadelman K.M.; Wong E.W.; Misaghian N.; Horn S.; Bäsecke J.; Libra M.; Stivala F.; Ligresti G.; Tafuri A.; Milella M.; Zarzycki M.; Dzugaj A.; Chiarini F.; Evangelisti C.; Martelli A.M.; Terrian D.M.; Franklin R.A.; Steelman L.S. | 2008-01-01 | - | Elsevier Ltd. | 2.01 Capitolo / saggio in libro | - |
| AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. | Grimaldi C.; Chiarini F.; Tabellini G.; Ricci F.; Tazzari P.L.; Battistelli M.; Falcieri E.; Bort...ul R.; Melchionda F.; Iacobucci I.; Pagliaro P.; Martinelli G.; Pession A.; Barata J.T.; McCubrey J.A.; Martelli A.M. | 2012-01-01 | LEUKEMIA | - | 1.01 Articolo in rivista | - |
| Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation | A. Cappellini; P.L. Tazzari; I. Mantovani; A.M. Billi; C. Tassi; F. Ricci; R. Conte; A.M. Martelli | 2005-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| Antioxidants in the prevention of UVB-induced keratynocyte apoptosis. | S. Salucci; S. Burattini; D. Curzi; F. Buontempo; A.M. Martelli; G. Zappia; E. Falcieri; M. Batti...stelli. | 2014-01-01 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | - | 1.01 Articolo in rivista | - |
| Application of flow cytometry to molecular medicine: Detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts | Cappellini A; Mantovani I; Tazzari PL; Grafone T; Martinelli G; Cocco L; Martelli AM | 2005-01-01 | INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | - | 1.01 Articolo in rivista | - |