Sfoglia per Autore
- Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors.
2016 Angela, De Simone; Andrea, Milelli; Marina, Naldi; Vincenza, Andrisano
Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors.
2016 De Simone, A; Milelli, A; Naldi, M; Andrisano, V.
Multifunctional activity of some isoquinoline alkaloids from Corydalis cava tubers on Alzheimer's disease targets
2016 Chlebek, J; De Simone, A; Pérez, Di; Pérez, C; Havlíková, L; Hošťálková, A; Opletal, L; Cahlíková, L; Andrisano, V
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors
2016 Di Martino, Rita Maria Concetta; De Simone, Angela; Andrisano, Vincenza; Bisignano, Paola; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Fato, Romana; Bergamini, Christian; Perez, Daniel I.; Martinez, Ana; Bottegoni, Giovanni; Cavalli, Andrea; Belluti, Federica
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment
2016 Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Concetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimers Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography
2016 Zha, Xiaoming; Lamba, Doriano; Zhang, Lili; Lou, Yinghan; Xu, Changxu; Kang, Di; Chen, Li; Xu, Yungen; Zhang, Luyong; De Simone, Angela; Samez, Sarah; Pesaresi, Alessandro; Stojan, Jure; Lopez, Manuela G.; Egea, Javier; Andrisano, Vincenza; Bartolini, Manuela
Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD)
2016 D'Urzo, Annalisa; DE SIMONE, Angela; Fiori, Jessica; Naldi, Marina; Milelli, Andrea; Andrisano, Vincenza
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets
2016 Chlebek, Jakub; De Simone, Angela; Hoš͗álková, Anna; Opletal, Lubomír; Pérez, Concepción; Pérez, Daniel I.; Havlíková, Lucie; Cahlíková, Lucie; Andrisano, Vincenza
Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development
2017 Milelli, Andrea; De Simone, Angela; Ticchi, Nicole; Chen, Huan Huan; Betari, Nibal; Andrisano, Vincenza; Tumiatti, Vincenzo
Uleine disrupts key enzymatic and non-enzymatic biomarkers that leads to Alzheimer's disease
2017 Seidl, Cláudia; de Moraes Santos, Cid Aimbiré; De Simone, Angela; Bartolini, Manuela; Weffort-Santos, Almeriane Maria; Andrisano, Vincenza
Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids
2017 Pérez-Areales, Francisco Javier; Betari, Nibal; Viayna, Antonio; Pont, Caterina; Espargarã³, Alba; Bartolini, Manuela; DE SIMONE, Angela; Rinaldi Alvarenga, José Fernando; Pã©rez, Belã©n; Sabate, Raimon; Lamuela-Raventós, Rosa Maria; Andrisano, Vincenza; Luque, Francisco Javier; Muñoz-Torrero, Diego
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease
2017 De Simone, Angela; Bartolini, Manuela; Baschieri, Andrea; Apperley, Kim Y.P.; Chen, Huan Huan; Guardigni, Melissa; Montanari, Serena; Kobrlova, Tereza; Soukup, Ondrej; Valgimigli, Luca; Andrisano, Vincenza; Keillor, Jeffrey W.; Basso, Manuela; Milelli, Andrea
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors
2017 De Simone, Angela; Fiori, Jessica; Naldi, Marina; D'Urzo, Annalisa; Tumiatti, Vincenzo; Milelli, Andrea; Andrisano, Vincenza
Synthesis and pharmacological evaluation of a novel class of multi target Huprine-based anti-Alzheimer hybrids
2018 m BARTOLINI, a DE SIMONE, V ANDRISANO
A multi-methodological approach for the investigation of β-Amyloid-CORMs interaction: an LC-ESI/MS and Circular Dichroism study.
2018 de simone a, naldi m, tedesco d, bartolini m, andrisano v
Integrated analytical methodologies for Alzheimer's disease drug discovery
2018 Angela De Simone, Marina Naldi, Daniele Tedesco, Manuela Bartolini, Vincenza Andrisano
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death
2018 Manuela Basso; Huan Huan Chen; Debasmita Tripathy; Mariarosaria Conte; Kim Y. P. Apperley; Angela De Simone; Jeffrey W. Keillor; Rajiv Ratan; Angela Nebbioso; Federica Sarno; Lucia Altucci; Andrea Milelli.
β-Amyloid-CORMs interaction monitoring by LC-ESI/MS and Circular Dichroism studies
2018 A De Simone; M Naldi; D Tedesco; M Bartolini; V Andrisano
Simultaneous Multiple MS Binding Assays for the Dopamine, Norepinephrine, and Serotonin Transporters
2018 Neiens P, De Simone A, Höfner G, Wanner KT
A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017
2018 Andrisano, Vincenza*; Naldi, Marina; De Simone, Angela; Bartolini, Manuela
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| - Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. | Angela, De Simone; Andrea, Milelli; Marina, Naldi; Vincenza, Andrisano | 2016-01-01 | - | - | 4.03 Poster | - |
| Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. | De Simone, A; Milelli, A; Naldi, M; Andrisano, V. | 2016-01-01 | - | - | 4.03 Poster | - |
| Multifunctional activity of some isoquinoline alkaloids from Corydalis cava tubers on Alzheimer's disease targets | Chlebek, J; De Simone, A; Pérez, Di; Pérez, C; Havlíková, L; Hošťálková, A; Opletal, L; Cahlíková..., L; Andrisano, V | 2016-01-01 | PLANTA MEDICA | - | 1.01 Articolo in rivista | - |
| Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors | Di Martino, Rita Maria Concetta; De Simone, Angela; Andrisano, Vincenza; Bisignano, Paola; Bisi, ...Alessandra; Gobbi, Silvia; Rampa, Angela; Fato, Romana; Bergamini, Christian; Perez, Daniel I.; Martinez, Ana; Bottegoni, Giovanni; Cavalli, Andrea; Belluti, Federica | 2016-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | AM11585-579953.pdf |
| Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment | Rampa, Angela; Tarozzi, Andrea; Mancini, Francesca; Pruccoli, Letizia; Di Martino, Rita Maria Con...cetta; Gobbi, Silvia; Bisi, Alessandra; De Simone, Angela; Palomba, Francesco; Zaccheroni, Nelsi; Belluti, Federica | 2016-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-21-00643.pdf |
| Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimers Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography | Zha, Xiaoming; Lamba, Doriano; Zhang, Lili; Lou, Yinghan; Xu, Changxu; Kang, Di; Chen, Li; Xu, Yu...ngen; Zhang, Luyong; De Simone, Angela; Samez, Sarah; Pesaresi, Alessandro; Stojan, Jure; Lopez, Manuela G.; Egea, Javier; Andrisano, Vincenza; Bartolini, Manuela | 2016-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Andrisano11585-550125.pdf |
| Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD) | D'Urzo, Annalisa; DE SIMONE, Angela; Fiori, Jessica; Naldi, Marina; Milelli, Andrea; Andrisano, V...incenza | 2016-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets | Chlebek, Jakub; De Simone, Angela; Hoš͗álková, Anna; Opletal, Lubomír; Pérez, Concepción; Pérez, ...Daniel I.; Havlíková, Lucie; Cahlíková, Lucie; Andrisano, Vincenza | 2016-01-01 | FITOTERAPIA | - | 1.01 Articolo in rivista | - |
| Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development | Milelli, Andrea; De Simone, Angela; Ticchi, Nicole; Chen, Huan Huan; Betari, Nibal; Andrisano, Vi...ncenza; Tumiatti, Vincenzo | 2017-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Uleine disrupts key enzymatic and non-enzymatic biomarkers that leads to Alzheimer's disease | Seidl, Cláudia; de Moraes Santos, Cid Aimbiré; De Simone, Angela; Bartolini, Manuela; Weffort-San...tos, Almeriane Maria; Andrisano, Vincenza | 2017-01-01 | CURRENT ALZHEIMER RESEARCH | - | 1.01 Articolo in rivista | - |
| Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids | Pérez-Areales, Francisco Javier; Betari, Nibal; Viayna, Antonio; Pont, Caterina; Espargarã³, Alb...a; Bartolini, Manuela; DE SIMONE, Angela; Rinaldi Alvarenga, José Fernando; Pã©rez, Belã©n; Sabate, Raimon; Lamuela-Raventós, Rosa Maria; Andrisano, Vincenza; Luque, Francisco Javier; Muñoz-Torrero, Diego | 2017-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease | De Simone, Angela; Bartolini, Manuela; Baschieri, Andrea; Apperley, Kim Y.P.; Chen, Huan Huan; Gu...ardigni, Melissa; Montanari, Serena; Kobrlova, Tereza; Soukup, Ondrej; Valgimigli, Luca; Andrisano, Vincenza; Keillor, Jeffrey W.; Basso, Manuela; Milelli, Andrea | 2017-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors | De Simone, Angela; Fiori, Jessica; Naldi, Marina; D'Urzo, Annalisa; Tumiatti, Vincenzo; Milelli, ...Andrea; Andrisano, Vincenza | 2017-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Synthesis and pharmacological evaluation of a novel class of multi target Huprine-based anti-Alzheimer hybrids | m BARTOLINI, a DE SIMONE, V ANDRISANO | 2018-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| A multi-methodological approach for the investigation of β-Amyloid-CORMs interaction: an LC-ESI/MS and Circular Dichroism study. | de simone a, naldi m, tedesco d, bartolini m, andrisano v | 2018-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Integrated analytical methodologies for Alzheimer's disease drug discovery | Angela De Simone, Marina Naldi, Daniele Tedesco, Manuela Bartolini, Vincenza Andrisano | 2018-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death |
Manuela Basso; Huan Huan Chen; Debasmita Tripathy; Mariarosaria Conte; Kim Y. P. Apperley; A...ngela De Simone; Jeffrey W. Keillor; Rajiv Ratan; Angela Nebbioso; Federica Sarno; Lucia Altucci; Andrea Milelli. |
2018-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | AM11585-621255.pdf |
| β-Amyloid-CORMs interaction monitoring by LC-ESI/MS and Circular Dichroism studies | A De Simone; M Naldi; D Tedesco; M Bartolini; V Andrisano | 2018-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Simultaneous Multiple MS Binding Assays for the Dopamine, Norepinephrine, and Serotonin Transporters | Neiens P, De Simone A, Höfner G, Wanner KT | 2018-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017 | Andrisano, Vincenza*; Naldi, Marina; De Simone, Angela; Bartolini, Manuela | 2018-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
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