Sfoglia per Autore
Optimization of natural compounds on-line screening by immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER).
2013 De Simone, A.; Seidl, C.; Santos, C.; Andrisano, V.
Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors
2013 Angela De Simone;Francesca Mancini;Feliciana Real Fernàndez;Paolo Rovero;Carlo Bertucci;Vincenza Andrisano
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease
2013 Federica Prati;Manuela Bartolini;Elena Simoni;Angela De Simone;Antonella Pinto;Vincenza Andrisano;Maria Laura Bolognesi
Monitoring GSM peptide phosphorylation by Glycogen Synthase Kinase-3β using Electrospray Ionization Ion Trap Mass Spectrometry (ESI-IT-MS).
2013 D’Urzo A.; Fiori J.; De Simone A.; Andrisano V.
Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library
2013 Angela De Simone;Francesca Mancini;Sandro Cosconati;Luciana Marinelli;Valeria La Pietra;Ettore Novellino;Vincenza Andrisano
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease
2014 Belluti F.; De Simone A.; Tarozzi A.; Bartolini M.; Djemil A.; Bisi A.; Gobbi S.; Montanari S.; Cavalli A.; Andrisano V.; Bottegoni G.; Rampa A.
ESI-MS and UHPLC combined analytical approaches for determining the kinetics of Glycogen Synthase Kinase-3β
2014 D’Urzo, A.; De Simone, A.; Fiori, J.; Andrisano, V.
Synthesis, in vitro biological profiling and in vivo efficacy studies of novel multitarget disease-modifyng anti-Alzheimer drug candidates.
2014 Diego Muñoz-Torrero; Irene Sola; Elisabet Viayna; Manuela Bartolini; Angela De Simone; Cheril Tapia-Rojas; Felipe G. Serrano; Raimon Sabaté; Jordi Juárez-Jiménez; Belén Pérez; F. Javier Luque; Vincenza Andrisano; M. Victòria Clos; Nibaldo C. Inestrosa
Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase.
2014 Gurjar AS; Andrisano V; De Simone A; Velingkar VS
Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents.
2014 Viayna E.; Sola I.; Bartolini M.; De Simone A.; Tapia-Rojas C.; Serrano F.G.; Sabaté R.; Juárez-Jiménez J.; Pérez B.; Luque F.J.; Andrisano V.; Clos M.V.; Inestrosa N.C.; Muñoz-Torrero D.
Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid as fluorogenic substrate
2014 Angela De Simone; Claudia Seidl; Cid A. Santos; Vincenza Andrisano
Analytical approaches in Alzheimer’s disease Drug Discovery
2015 De Simone, Angela; Bartolini, Manuela; Fiori, Jessica; D’Urzo, Annalisa; Naldi, Marina.; Andrisano, Vincenza
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease
2015 Prati, Federica; De Simone, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpelli, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez-Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, Maria L.
Characterization of essential oil components in cosmetic products by GC-MS.
2015 De Simone, A.; Andrisano, V.
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold
2015 Angela, Rampa; Francesca, Mancini; Angela, De Simone; Federico, Falchi; Federica, Belluti; Rita Maria, Concetta Di Martino; Silvia, Gobbi; Vincenza, Andrisano; Andrea, Tarozzi; Manuela, Bartolini; Andrea, Cavalli; Alessandra, Bisi
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors.
2015 Prati F;De Simone A;Bisignano P;Armirotti A;Summa M;Pizzirani D;Scarpelli R;Perez DI;Andrisano V;Perez-Castillo A;Monti B;Massenzio F;Polito L;Racchi M;Favia AD;Bottegoni G;Martinez A;Bolognesi ML;Cavalli A
Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici.
2016 De Simone, A; Naldi, M; Milelli, A; Andrisano, V
Design, Synthesis and Biological profiling of a promising new family of multitarget directed ligands for the treatment of Alzheimer Disease.
2016 Pérez-Areales JF; Bartolini M; De Simone A; Espergaro A; Sabaté R; Pérez B; Andrisano V; Luque FJ; Messeguer A; Munoz-Torrero D.
The role of Chromatography in Alzheimer’s Disease Drug Discovery.
2016 Fiori, J; De Simone, A; Naldi, M; Andrisano, V
Simultaneous MS Binding Assays for Monoamine Transporters.
2016 Neiens P; De Simone A; Höfner G; Wanner KT.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Optimization of natural compounds on-line screening by immobilized enzyme reactor based on human recombinant betasecretase (hrBACE-1-IMER). | De Simone, A.; Seidl, C.; Santos, C.; Andrisano, V. | 2013-01-01 | - | - | 4.03 Poster | - |
| Surface plasmon resonance, fluorescence, and circular dichroism studies for the characterization of the binding of BACE-1 inhibitors | Angela De Simone;Francesca Mancini;Feliciana Real Fernàndez;Paolo Rovero;Carlo Bertucci;Vincenza ...Andrisano | 2013-01-01 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease | Federica Prati;Manuela Bartolini;Elena Simoni;Angela De Simone;Antonella Pinto;Vincenza Andrisano...;Maria Laura Bolognesi | 2013-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Monitoring GSM peptide phosphorylation by Glycogen Synthase Kinase-3β using Electrospray Ionization Ion Trap Mass Spectrometry (ESI-IT-MS). | D’Urzo A.; Fiori J.; De Simone A.; Andrisano V. | 2013-01-01 | - | - | 4.03 Poster | - |
| Human recombinant beta-secretase immobilized enzyme reactor for fast hits’ selection and characterization from a virtual screening library | Angela De Simone;Francesca Mancini;Sandro Cosconati;Luciana Marinelli;Valeria La Pietra;Ettore No...vellino;Vincenza Andrisano | 2013-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease | Belluti F.; De Simone A.; Tarozzi A.; Bartolini M.; Djemil A.; Bisi A.; Gobbi S.; Montanari S.; C...avalli A.; Andrisano V.; Bottegoni G.; Rampa A. | 2014-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| ESI-MS and UHPLC combined analytical approaches for determining the kinetics of Glycogen Synthase Kinase-3β | D’Urzo, A.; De Simone, A.; Fiori, J.; Andrisano, V. | 2014-01-01 | - | - | 4.03 Poster | - |
| Synthesis, in vitro biological profiling and in vivo efficacy studies of novel multitarget disease-modifyng anti-Alzheimer drug candidates. | Diego Muñoz-Torrero; Irene Sola; Elisabet Viayna; Manuela Bartolini; Angela De Simone; Cheril Tap...ia-Rojas; Felipe G. Serrano; Raimon Sabaté; Jordi Juárez-Jiménez; Belén Pérez; F. Javier Luque; Vincenza Andrisano; M. Victòria Clos; Nibaldo C. Inestrosa | 2014-01-01 | - | - | 4.03 Poster | - |
| Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase. | Gurjar AS; Andrisano V; De Simone A; Velingkar VS | 2014-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents. | Viayna E.; Sola I.; Bartolini M.; De Simone A.; Tapia-Rojas C.; Serrano F.G.; Sabaté R.; Juárez-J...iménez J.; Pérez B.; Luque F.J.; Andrisano V.; Clos M.V.; Inestrosa N.C.; Muñoz-Torrero D. | 2014-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid as fluorogenic substrate | Angela De Simone; Claudia Seidl; Cid A. Santos; Vincenza Andrisano | 2014-01-01 | JOURNAL OF CHROMATOGRAPHY B | - | 1.01 Articolo in rivista | - |
| Analytical approaches in Alzheimer’s disease Drug Discovery | De Simone, Angela; Bartolini, Manuela; Fiori, Jessica; D’Urzo, Annalisa; Naldi, Marina.; Andrisan...o, Vincenza | 2015-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease | Prati, Federica; De Simone, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpell...i, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez-Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, Maria L. | 2015-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | accepted11585-546374.pdf |
| Characterization of essential oil components in cosmetic products by GC-MS. | De Simone, A.; Andrisano, V. | 2015-01-01 | - | - | 4.03 Poster | - |
| From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold | Angela, Rampa; Francesca, Mancini; Angela, De Simone; Federico, Falchi; Federica, Belluti; Rita M...aria, Concetta Di Martino; Silvia, Gobbi; Vincenza, Andrisano; Andrea, Tarozzi; Manuela, Bartolini; Andrea, Cavalli; Alessandra, Bisi | 2015-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors. | Prati F;De Simone A;Bisignano P;Armirotti A;Summa M;Pizzirani D;Scarpelli R;Perez DI;Andrisano V;...Perez-Castillo A;Monti B;Massenzio F;Polito L;Racchi M;Favia AD;Bottegoni G;Martinez A;Bolognesi ML;Cavalli A | 2015-01-01 | ANGEWANDTE CHEMIE. INTERNATIONAL EDITION | - | 1.01 Articolo in rivista | - |
| Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici. | De Simone, A; Naldi, M; Milelli, A; Andrisano, V | 2016-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| Design, Synthesis and Biological profiling of a promising new family of multitarget directed ligands for the treatment of Alzheimer Disease. | Pérez-Areales JF; Bartolini M; De Simone A; Espergaro A; Sabaté R; Pérez B; Andrisano V; Luque FJ...; Messeguer A; Munoz-Torrero D. | 2016-01-01 | - | - | 4.03 Poster | - |
| The role of Chromatography in Alzheimer’s Disease Drug Discovery. | Fiori, J; De Simone, A; Naldi, M; Andrisano, V | 2016-01-01 | - | Taylor & Francis Group | 2.01 Capitolo / saggio in libro | - |
| Simultaneous MS Binding Assays for Monoamine Transporters. | Neiens P; De Simone A; Höfner G; Wanner KT. | 2016-01-01 | - | - | 4.03 Poster | - |
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