Sfoglia per Autore
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer.
2008 V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases
2008 A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre
Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library
2008 Bolognesi ML; Calonghi N; Mangano C; Masotti L; Melchiorre C.
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease
2008 M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update
2008 V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics
2008 A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre
Polymethylene tetraamine backbone as template for the development of biologically active polyamines
2009 A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease
2009 M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre
Cytotoxicity of methoctramine and methoctramine-related polyamines.
2009 Zini M.; Passariello C.L.; Gottardi D.; Cetrullo S.; Flamigni F.; Pignatti C.; Minarini A.; Tumiatti V.; Milelli A.; Melchiorre C.; Stefanelli C.
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action
2009 Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C.
Alzheimer's disease: new approaches to drug discovery.
2009 Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C.
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks
2009 Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchiorre C.
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease
2009 Bolognesi ML; Cavalli A; Melchiorre C.
Organic compounds useful for the treatment of neurodegenerative diseases, uses and methods for the preparation thereof
2009 M.L. Bolognesi; A. Cavalli; M. Recanatini; C. Melchiorre
Preparation of 2,5-bis-diamine-[1,4]benzoquinone derivatives for the treatment of Alzheimer's disease and a process for their preparation and intermediates thereof.
2009 Andrisano V.; Bartolini M.; Bolognesi M.L.; Cavalli A.; Melchiorre C.; Recanatini M.
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents
2009 V. Tumiatti; A. Milelli; A. Minarini; M. Micco; A. Gasperi Campani; L. Roncuzzi; D. Baiocchi; M. Zini; C. Stefanelli; C. Melchiorre
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond
2009 Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C.
Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease.
2009 Mancini F.; Bolognesi M.L.; Melchiorre C.; Andrisano V.
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT
2009 Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C
Doxazosin-related alpha1-adrenoceptor antagonists with prostate antitumor activity
2009 Giardinà D.; Martarelli D.; Sagratini G.; Angeli P.; Ballinari D.; Gulini U.; Melchiorre C.; Poggesi E.; Pompei P.
Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
---|---|---|---|---|---|---|
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. | V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bart...olini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases | A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Parallel synthesis and cytotoxicity evaluation of a polyamine-quinone conjugates library | Bolognesi ML; Calonghi N; Mangano C; Masotti L; Melchiorre C. | 2008-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease | M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre | 2008-01-01 | MINI-REVIEWS IN MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update | V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre | 2008-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics | A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosi...ni; C. Melchiorre | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Polymethylene tetraamine backbone as template for the development of biologically active polyamines | A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre | 2009-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease | M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatt...i; V. Andrisano; I. R. Mellor; C. Melchiorre | 2009-01-01 | DRUGS OF THE FUTURE | - | 4.02 Riassunto (Abstract) | - |
Cytotoxicity of methoctramine and methoctramine-related polyamines. | Zini M.; Passariello C.L.; Gottardi D.; Cetrullo S.; Flamigni F.; Pignatti C.; Minarini A.; Tumia...tti V.; Milelli A.; Melchiorre C.; Stefanelli C. | 2009-01-01 | CHEMICO-BIOLOGICAL INTERACTIONS | - | 1.01 Articolo in rivista | - |
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action | Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C. | 2009-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
Alzheimer's disease: new approaches to drug discovery. | Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C. | 2009-01-01 | CURRENT OPINION IN CHEMICAL BIOLOGY | - | 1.01 Articolo in rivista | - |
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks | Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchi...orre C. | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease | Bolognesi ML; Cavalli A; Melchiorre C. | 2009-01-01 | NEUROTHERAPEUTICS | - | 1.01 Articolo in rivista | - |
Organic compounds useful for the treatment of neurodegenerative diseases, uses and methods for the preparation thereof | M.L. Bolognesi; A. Cavalli; M. Recanatini; C. Melchiorre | 2009-01-01 | - | - | 6.01 Brevetto | - |
Preparation of 2,5-bis-diamine-[1,4]benzoquinone derivatives for the treatment of Alzheimer's disease and a process for their preparation and intermediates thereof. | Andrisano V.; Bartolini M.; Bolognesi M.L.; Cavalli A.; Melchiorre C.; Recanatini M. | 2009-01-01 | - | - | 6.01 Brevetto | - |
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents | V. Tumiatti; A. Milelli; A. Minarini; M. Micco; A. Gasperi Campani; L. Roncuzzi; D. Baiocchi; M. ...Zini; C. Stefanelli; C. Melchiorre | 2009-01-01 | DRUGS OF THE FUTURE | - | 4.02 Riassunto (Abstract) | - |
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond | Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C. | 2009-01-01 | CURRENT PHARMACEUTICAL DESIGN | - | 1.01 Articolo in rivista | - |
Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease. | Mancini F.; Bolognesi M.L.; Melchiorre C.; Andrisano V. | 2009-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT | Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello... J; Capranico G; Zini M; Stefanelli C; Melchiorre C | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
Doxazosin-related alpha1-adrenoceptor antagonists with prostate antitumor activity | Giardinà D.; Martarelli D.; Sagratini G.; Angeli P.; Ballinari D.; Gulini U.; Melchiorre C.; Pogg...esi E.; Pompei P. | 2009-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
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