Unseen adversary: Navigating the drucebo effect in neurological treatments

The drucebo effect, introduced to describe adverse reactions driven by patients’ expectations rather than the pharmacological action of drugs, significantly impacts neurological treatments. This phenomenon manifests through symptoms triggered by anticipated side effects, which can hinder therapeutic adherence and reduce effectiveness. Managing the drucebo effect requires effective communication to mitigate negative expectations. This article presents a step-by-step approach, the Personalized Neurological Intervention Plan (PNIP), aiming to address patient perceptions and improve adherence in neurological care. Future research should refine strategies for personalized interventions to minimize this impact.