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EnglishSUMMARY - Transcripts for sweet and bitter taste receptors and the gustatory G proteins, alpha-gustducin and alpha-transducin, are expressed by the oral cavity and the gastrointestinal (GI) mucosa. This study evaluated: 1) distribution of alpha-transducin in the pig GI tract; 2) type of cells expressing alpha-transducin (chromogranin-A, gastrin/cholecystokinin, somatostatin, villin) 3) relationship between alpha-transducin cells and enteric fibres. The presence of alpha-transducin-IR in enteroendocrine cells supports an active chemosensory machinery in the GI mucosa and that taste signalling molecules contribute to luminal chemosensing. These mechanisms may occur via neuro-endocrine cross-talk activating digestive or protective reflex pathways (e.g. vomiting or food aversion).
| Titolo: | Espressione dell’ α-transducina, una molecola della chemorecezione, in cellule endocrine e non endocrine del tratto gastrointestinale di suino. | |
| Autore/i: | CLAVENZANI, PAOLO; DE GIORGIO, ROBERTO; MAZZONI, MAURIZIO; CHIOCCHETTI, ROBERTO; BARBARA, GIOVANNI; LALATTA COSTERBOSA, GIOVANNA; RUSSO D.; STERNINI C. | |
| Autore/i Unibo: | ||
| Anno: | 2008 | |
| Titolo del libro: | Atti LXII Conv. Naz. S.I.S.Vet. | |
| Pagina iniziale: | 5 | |
| Pagina finale: | 6 | |
| Abstract: | SUMMARY - Transcripts for sweet and bitter taste receptors and the gustatory G proteins, alpha-gustducin and alpha-transducin, are expressed by the oral cavity and the gastrointestinal (GI) mucosa. This study evaluated: 1) distribution of alpha-transducin in the pig GI tract; 2) type of cells expressing alpha-transducin (chromogranin-A, gastrin/cholecystokinin, somatostatin, villin) 3) relationship between alpha-transducin cells and enteric fibres. The presence of alpha-transducin-IR in enteroendocrine cells supports an active chemosensory machinery in the GI mucosa and that taste signalling molecules contribute to luminal chemosensing. These mechanisms may occur via neuro-endocrine cross-talk activating digestive or protective reflex pathways (e.g. vomiting or food aversion). | |
| Data prodotto definitivo in UGOV: | 21-feb-2011 | |
| Appare nelle tipologie: | 4.01 Contributo in Atti di convegno |
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