The use of oral anticoagulant drugs has increased in recent years, leading to reports of possible adverse effects. Anticoagulant-related nephropathy (ARN) is a cause of acute kidney injury (AKI) associated with both older and newer anticoagulant agents. The underlying pathogenetic mechanism is not completely understood, but some common risk factors, such as pre-existing renal damage, have been identified. Renal biopsy can help recognize typical but nonspecific lesions. Here, we report the case of a patient with severe renal and systemic involvement while on apixaban therapy.
Vischini G., Speciale S., Przygocka A., Martano L., La Manna G., Baraldi O. (2024). Lessons for the clinical nephrologist: acute kidney injury during therapy with apixaban. JN. JOURNAL OF NEPHROLOGY, 37(2), 511-513 [10.1007/s40620-023-01781-y].
Lessons for the clinical nephrologist: acute kidney injury during therapy with apixaban
Speciale S.
;Przygocka A.
;Martano L.
;La Manna G.
;Baraldi O.
2024
Abstract
The use of oral anticoagulant drugs has increased in recent years, leading to reports of possible adverse effects. Anticoagulant-related nephropathy (ARN) is a cause of acute kidney injury (AKI) associated with both older and newer anticoagulant agents. The underlying pathogenetic mechanism is not completely understood, but some common risk factors, such as pre-existing renal damage, have been identified. Renal biopsy can help recognize typical but nonspecific lesions. Here, we report the case of a patient with severe renal and systemic involvement while on apixaban therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.