The use of oral anticoagulant drugs has increased in recent years, leading to reports of possible adverse effects. Anticoagulant-related nephropathy (ARN) is a cause of acute kidney injury (AKI) associated with both older and newer anticoagulant agents. The underlying pathogenetic mechanism is not completely understood, but some common risk factors, such as pre-existing renal damage, have been identified. Renal biopsy can help recognize typical but nonspecific lesions. Here, we report the case of a patient with severe renal and systemic involvement while on apixaban therapy.
Vischini, G., Speciale, S., Przygocka, A., Martano, L., La Manna, G., Baraldi, O. (2024). Lessons for the clinical nephrologist: acute kidney injury during therapy with apixaban. JN. JOURNAL OF NEPHROLOGY, 37(2), 511-513 [10.1007/s40620-023-01781-y].
Lessons for the clinical nephrologist: acute kidney injury during therapy with apixaban
Speciale S.;Przygocka A.;Martano L.;La Manna G.
;Baraldi O.
2024
Abstract
The use of oral anticoagulant drugs has increased in recent years, leading to reports of possible adverse effects. Anticoagulant-related nephropathy (ARN) is a cause of acute kidney injury (AKI) associated with both older and newer anticoagulant agents. The underlying pathogenetic mechanism is not completely understood, but some common risk factors, such as pre-existing renal damage, have been identified. Renal biopsy can help recognize typical but nonspecific lesions. Here, we report the case of a patient with severe renal and systemic involvement while on apixaban therapy.| File | Dimensione | Formato | |
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