[GRAPHICS]Cerium(III) chloride heptahydrate and sodium iodide in boiling acetonitrile promote cyclization of 3-hydroxyalkenoic acids esters giving 5-substituted tetrahydrofuranacetic acid esters and 6-substituted tetrahydropyranacetic acid esters in fair to good yield and with complete retention of the absolute configuration of the starting 3-hydroxy ester.
CeCl3·7H2O−NaI Catalyzed Hydrooxacyclization of Unsaturated 3-Hydroxy Esters / Marotta, Emanuela; Foresti, Elisabetta; Marcelli, Tommaso; Peri, Francesca; Righi, Paolo; Scardovi, Noemi; Rosini, Goffredo. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 4:25(2002), pp. 4451-4453. [10.1021/ol026955z]
CeCl3·7H2O−NaI Catalyzed Hydrooxacyclization of Unsaturated 3-Hydroxy Esters
Marotta, Emanuela;Foresti, Elisabetta;Peri, Francesca;Righi, Paolo;Scardovi, Noemi;Rosini, Goffredo
2002
Abstract
[GRAPHICS]Cerium(III) chloride heptahydrate and sodium iodide in boiling acetonitrile promote cyclization of 3-hydroxyalkenoic acids esters giving 5-substituted tetrahydrofuranacetic acid esters and 6-substituted tetrahydropyranacetic acid esters in fair to good yield and with complete retention of the absolute configuration of the starting 3-hydroxy ester.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
