Enantiomers of endo-bicyclo[3.3.0]oct-7-en-2-ol have been resolved by an efficient and practical procedure based on the utilisation of (2S)- and (2R)-1-(4-toluenesulphonyl)pyrrolidine-2-carboxylic acid chlorides [(2S)-NTP-Cl and (2R)-NTP-Cl], easily available from, respectively, (2S)- and (2R)-proline, as resolving agents.
Marotta, E., Rastelli, E., Righi, P., Rosini, G. (1993). A practical preparation of pure enantiomers of endo-bicyclo[3.3.0]oct-7-en-2-ol, versatile intermediate for the synthesis of natural products. TETRAHEDRON-ASYMMETRY, 4(4), 735-742 [10.1016/s0957-4166(00)80182-2].
A practical preparation of pure enantiomers of endo-bicyclo[3.3.0]oct-7-en-2-ol, versatile intermediate for the synthesis of natural products
Marotta, Emanuela;Righi, Paolo;Rosini, Goffredo
1993
Abstract
Enantiomers of endo-bicyclo[3.3.0]oct-7-en-2-ol have been resolved by an efficient and practical procedure based on the utilisation of (2S)- and (2R)-1-(4-toluenesulphonyl)pyrrolidine-2-carboxylic acid chlorides [(2S)-NTP-Cl and (2R)-NTP-Cl], easily available from, respectively, (2S)- and (2R)-proline, as resolving agents.File in questo prodotto:
Eventuali allegati, non sono esposti
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
