The present invention provides a method for the preparation of icatibant comprising a chromatographic process for removing impurities from a solution containing icatibant with a purity below specification, wherein fractions corresponding to overlapping regions, containing both icatibant and impurities, are recycled and undergo further purification together with amounts of the original feed solution in an iterative process.
METHOD FOR ICATIBANT PREPARATION
Cabri,W.;
2021
Abstract
The present invention provides a method for the preparation of icatibant comprising a chromatographic process for removing impurities from a solution containing icatibant with a purity below specification, wherein fractions corresponding to overlapping regions, containing both icatibant and impurities, are recycled and undergo further purification together with amounts of the original feed solution in an iterative process.File in questo prodotto:
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