: The overall burden of the main clinically relevant bacterial multidrug-resistant organisms (MDROs) (eg, methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum β-lactamase producing or extended-spectrum cephalosporin-resistant Enterobacterales, carbapenem-resistant or carbapenemase-producing Enterobacterales, MDR Pseudomonas aeruginosa, and carbapenem-resistant Acinetobacter baumannii) in solid organ transplant (SOT) populations is summarized showing prevalence/incidence, risk factors, and impact on graft/patient outcome according to the type of SOT. The role of such bacteria in donor-derived infections is also reviewed. As for the management, the main prevention strategies and treatment options are discussed. Finally, nonantibiotic-based strategies are considered as future directions for the management of MDRO in SOT setting.

Giannella M., Rinaldi M., Viale P. (2023). Antimicrobial Resistance in Organ Transplant Recipients. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 37(3), 515-537 [10.1016/j.idc.2023.04.001].

Antimicrobial Resistance in Organ Transplant Recipients

Giannella M.
;
Rinaldi M.;Viale P.
2023

Abstract

: The overall burden of the main clinically relevant bacterial multidrug-resistant organisms (MDROs) (eg, methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum β-lactamase producing or extended-spectrum cephalosporin-resistant Enterobacterales, carbapenem-resistant or carbapenemase-producing Enterobacterales, MDR Pseudomonas aeruginosa, and carbapenem-resistant Acinetobacter baumannii) in solid organ transplant (SOT) populations is summarized showing prevalence/incidence, risk factors, and impact on graft/patient outcome according to the type of SOT. The role of such bacteria in donor-derived infections is also reviewed. As for the management, the main prevention strategies and treatment options are discussed. Finally, nonantibiotic-based strategies are considered as future directions for the management of MDRO in SOT setting.
2023
Giannella M., Rinaldi M., Viale P. (2023). Antimicrobial Resistance in Organ Transplant Recipients. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 37(3), 515-537 [10.1016/j.idc.2023.04.001].
Giannella M.; Rinaldi M.; Viale P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/962487
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