Since fat-free tissues are responsible for 95% of basal energy expenditure, fat-free mass is expected to be a better determinant of thyroid size and function than anthropometry. We tested the hypothesis that fat-free tissues as qualitatively determined by body resistance (R) at 50 kHz are more strongly associated with TSH than anthropometric indicators in healthy subjects. A number of 78 euthyroid adults of both sexes were consecutively studied. R was the best single predictor of TSH (R-adj(2)=0.65, p<0.0001). It explained 36% more variance than bw (R-adj(2)=0.29, p<0.0001), the most accurate anthropometric predictor. Sex had no effect on the relationship between TSH, bioelectrical impedance analysis and anthropometry. After the contribution of R to TSH was taken into account, anthropometric indicators were not able to explain any additional part of TSH variance. We conclude that in healthy subjects, bioelectrical resistance is a better indicator of thyroid function than anthropometry, probably because of its more direct relationship with fat-free tissues. Further studies are needed to test whether this relationship holds in under- and over-weight subjects. (C) 2002, Editrice Kurtis.
Thyroid function is more strongly associated with body impedance than anthropometry in healthy subjects / Sartorio, A; Ferrero, S; Trecate, L; Bedogni, G. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 0391-4097. - STAMPA. - 25:7(2002), pp. 620-623. [10.1007/BF03345086]
Thyroid function is more strongly associated with body impedance than anthropometry in healthy subjects
Bedogni, GUltimo
2002
Abstract
Since fat-free tissues are responsible for 95% of basal energy expenditure, fat-free mass is expected to be a better determinant of thyroid size and function than anthropometry. We tested the hypothesis that fat-free tissues as qualitatively determined by body resistance (R) at 50 kHz are more strongly associated with TSH than anthropometric indicators in healthy subjects. A number of 78 euthyroid adults of both sexes were consecutively studied. R was the best single predictor of TSH (R-adj(2)=0.65, p<0.0001). It explained 36% more variance than bw (R-adj(2)=0.29, p<0.0001), the most accurate anthropometric predictor. Sex had no effect on the relationship between TSH, bioelectrical impedance analysis and anthropometry. After the contribution of R to TSH was taken into account, anthropometric indicators were not able to explain any additional part of TSH variance. We conclude that in healthy subjects, bioelectrical resistance is a better indicator of thyroid function than anthropometry, probably because of its more direct relationship with fat-free tissues. Further studies are needed to test whether this relationship holds in under- and over-weight subjects. (C) 2002, Editrice Kurtis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.