Abstract: Background: Despite the growing interest in CO2 angiography, some mechanical aspects related to CO2 injection still need to be deepened, and some improvements are still possible. This work explores the possibility of optimizing gas injection into small-sized arteries. Since the image quality depends on how the gas fills the vessel and is strongly dependent on injection flow, the possibility of controlling the flow is mandatory to obtain good results. To better control the flow, we propose to adjunct small tubes with known hydraulic resistances in parallel to the injection catheter, allowing the generation of the desired injection flow by modulating the injection pressure. Methods: Using a mechanical mock of the cardiovascular system, we measured pressures and flows of interest and acquired the optical images of the vessel during gas injections. We performed a simulation with four different calibrated adjunct resistances in various injection pressure conditions, with and without saline flushing. Results: Our tests demonstrated that the optimized injection of the gas maintains the same procedure durations and reduces the gas volume and the local pressure increase, avoiding the local gas “explosion” in the injection site. Conclusions: Our proposal appears effective and paves the way for research into optimizing clinical CO2 angiography procedures.

Calibrated Hydraulic Resistance Adjuncts for Carbon Dioxide Angiography Optimization / Corazza, Ivan; Rossi, Pier Luca; Zannoli, Romano. - In: APPLIED SCIENCES. - ISSN 2076-3417. - ELETTRONICO. - 14:3(2024), pp. 1-12. [10.3390/app14031276]

Calibrated Hydraulic Resistance Adjuncts for Carbon Dioxide Angiography Optimization

Corazza, Ivan;Rossi, Pier Luca;Zannoli, Romano
2024

Abstract

Abstract: Background: Despite the growing interest in CO2 angiography, some mechanical aspects related to CO2 injection still need to be deepened, and some improvements are still possible. This work explores the possibility of optimizing gas injection into small-sized arteries. Since the image quality depends on how the gas fills the vessel and is strongly dependent on injection flow, the possibility of controlling the flow is mandatory to obtain good results. To better control the flow, we propose to adjunct small tubes with known hydraulic resistances in parallel to the injection catheter, allowing the generation of the desired injection flow by modulating the injection pressure. Methods: Using a mechanical mock of the cardiovascular system, we measured pressures and flows of interest and acquired the optical images of the vessel during gas injections. We performed a simulation with four different calibrated adjunct resistances in various injection pressure conditions, with and without saline flushing. Results: Our tests demonstrated that the optimized injection of the gas maintains the same procedure durations and reduces the gas volume and the local pressure increase, avoiding the local gas “explosion” in the injection site. Conclusions: Our proposal appears effective and paves the way for research into optimizing clinical CO2 angiography procedures.
2024
Calibrated Hydraulic Resistance Adjuncts for Carbon Dioxide Angiography Optimization / Corazza, Ivan; Rossi, Pier Luca; Zannoli, Romano. - In: APPLIED SCIENCES. - ISSN 2076-3417. - ELETTRONICO. - 14:3(2024), pp. 1-12. [10.3390/app14031276]
Corazza, Ivan; Rossi, Pier Luca; Zannoli, Romano
File in questo prodotto:
File Dimensione Formato  
applsci-14-01276.pdf

accesso aperto

Tipo: Versione (PDF) editoriale
Licenza: Licenza per Accesso Aperto. Creative Commons Attribuzione (CCBY)
Dimensione 4.9 MB
Formato Adobe PDF
4.9 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/959462
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 0
social impact