Patients with syndromic craniosynostosis have a molecularly identified genetic cause for the premature closure of their cranial sutures and associated facial and extra-cranial features. Their clinical complexity demands comprehensive management by an extensive multidisciplinary team. This review aims to marry genotypic and phenotypic knowledge with clinical presentation and management of the craniofacial syndromes presenting most frequently to the craniofacial unit at Great Ormond Street Hospital for Children NHS Foundation Trust. (c) 2019 S. Karger AG, Basel
O''Hara, J., Ruggiero, F., Wilson, L., James, G., Glass, G., Jeelani, O., et al. (2019). Syndromic Craniosynostosis: Complexities of Clinical Care. MOLECULAR SYNDROMOLOGY, 10(1-2), 83-97 [10.1159/000495739].
Syndromic Craniosynostosis: Complexities of Clinical Care
Ruggiero, FedericaCo-primo
;
2019
Abstract
Patients with syndromic craniosynostosis have a molecularly identified genetic cause for the premature closure of their cranial sutures and associated facial and extra-cranial features. Their clinical complexity demands comprehensive management by an extensive multidisciplinary team. This review aims to marry genotypic and phenotypic knowledge with clinical presentation and management of the craniofacial syndromes presenting most frequently to the craniofacial unit at Great Ormond Street Hospital for Children NHS Foundation Trust. (c) 2019 S. Karger AG, BaselI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
