We have read with great interest the paper oh Ha et al. which focuses on the importance of multi-matrixanalysis in gammahydroxybutyrate (GilB) postmortem toxicology and the usefulness of vitreous humor and brain tissue to distinguish exogenous GHB exposure from endogenous production. We agree with the authors on the importance of multi-matrix analysis for GHiB postmortem analysis, as also reported elsewhere, which "should possibly include the comparison of various biological conventional and non conventional matrices for a proper assessment of each case". Nevertheless,there are some points in Ha et al.'s study worthy of attention that we wish to discuss.
Pirani F., Busardo F.P. (2020). The Difficult Interpretation of GHB Values in Postmortem Samples: What Strategies Should Be Followed?. JOURNAL OF ANALYTICAL TOXICOLOGY, 44(9), 11-12 [10.1093/jat/bkaa130].
The Difficult Interpretation of GHB Values in Postmortem Samples: What Strategies Should Be Followed?
Pirani F.Primo
;
2020
Abstract
We have read with great interest the paper oh Ha et al. which focuses on the importance of multi-matrixanalysis in gammahydroxybutyrate (GilB) postmortem toxicology and the usefulness of vitreous humor and brain tissue to distinguish exogenous GHB exposure from endogenous production. We agree with the authors on the importance of multi-matrix analysis for GHiB postmortem analysis, as also reported elsewhere, which "should possibly include the comparison of various biological conventional and non conventional matrices for a proper assessment of each case". Nevertheless,there are some points in Ha et al.'s study worthy of attention that we wish to discuss.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
