Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) showed significant improvement in providing valuable insights to the elemental distribution within solid materials in terms of lateral resolution and data acquisition speed. Furthermore, the use of the time-of-flight (TOF) mass analyzer and its capabilities for fast and simultaneous multi-element detection made this technique more versatile and attractive for many applications. Yet a tight integration of the different components (translation stage, laser, and ICP-MS) allows more advanced modes of operation which increase sensitivity with maximal 2D and 3D resolution. In this work we present a software suite specifically developed for conducting and processing LA-ICP-MS imaging experiments. The end to end solution allows for custom ablation area masks to be imaged fitting the sample structure. Furthermore, laser pulse patterns are freely programmable: high spatial resolution fast imaging with edge-to-edge laser spots ideal for compositional overview or hole drilling for increased sensitivity. The quantitative data analysis workflow is highly customizable and interfaces are provided for new algorithms to integrated by the user. We exemplify our approach by quantitative element imaging of a geological sample. All experiments were performed with a GeoLas C (193 nm excimer laser, Lambda Physik, Goettingen, Germany), an in-house build low dispersion ablation cell, and ICP-TOFMS (icpTOF, TOFWERK, Thun, Switzerland).
A Versatile Software Suite for Advanced Laser Ablation ICP-MS Element Imaging / Keresztes Schmidt P.; Neff C.; Schwarz G.; Garofalo P. S.; Hattendorf B.; Günther D.. - In: CHIMIA. - ISSN 0009-4293. - STAMPA. - (2019). (Intervento presentato al convegno CHanalysis 2019 tenutosi a Beatenberg, Svizzera nel April 10th–11th, 2019).
A Versatile Software Suite for Advanced Laser Ablation ICP-MS Element Imaging
Garofalo P. S.Membro del Collaboration Group
;
2019
Abstract
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) showed significant improvement in providing valuable insights to the elemental distribution within solid materials in terms of lateral resolution and data acquisition speed. Furthermore, the use of the time-of-flight (TOF) mass analyzer and its capabilities for fast and simultaneous multi-element detection made this technique more versatile and attractive for many applications. Yet a tight integration of the different components (translation stage, laser, and ICP-MS) allows more advanced modes of operation which increase sensitivity with maximal 2D and 3D resolution. In this work we present a software suite specifically developed for conducting and processing LA-ICP-MS imaging experiments. The end to end solution allows for custom ablation area masks to be imaged fitting the sample structure. Furthermore, laser pulse patterns are freely programmable: high spatial resolution fast imaging with edge-to-edge laser spots ideal for compositional overview or hole drilling for increased sensitivity. The quantitative data analysis workflow is highly customizable and interfaces are provided for new algorithms to integrated by the user. We exemplify our approach by quantitative element imaging of a geological sample. All experiments were performed with a GeoLas C (193 nm excimer laser, Lambda Physik, Goettingen, Germany), an in-house build low dispersion ablation cell, and ICP-TOFMS (icpTOF, TOFWERK, Thun, Switzerland).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
