Objectives: It is acknowledged that living in a green environment may help mental well-being and this may be especially true for vulnerable people. However, the relationship between greenness and neuropsychiatric symptoms in dementia has not been explored yet. Methods: We collected clinical, neuropsychiatric, and residential data from subjects with dementia living in the province of Modena, Northern Italy. Neuropsychiatric symptoms were measured with the Neuropsychiatry Inventory, a questionnaire administered to the caregiver who assesses the presence and severity of neuropsychiatric symptoms, including delusions, hallucinations, agitation/aggression, dysphoria/depression, anxiety, euphoria/elation, apathy/indifference, disinhibition, irritability/lability, aberrant motor behaviors, sleep disturbances, and appetite/eating changes. Normalized Difference Vegetation Index (NDVI) was used as a proxy of greenness. Regression models were constructed to study the association between greenness and neuropsychiatric features. Results: 155 patients with dementia were recruited. We found that greenness is variably associated with the risk of having neuropsychiatric symptoms. The risk of apathy was lower with lower levels of greenness (OR = 0.42, 95% CI 0.19-0.91 for NDVI below the median value). The risk of psychosis was higher with lower levels of greenness but with more imprecise values (OR = 1.77, 95% CI 0.84-3.73 for NDVI below the median value). Conclusion: Our results suggest a possible association between greenness and neuropsychiatric symptoms in people with dementia. If replicated in larger samples, these findings will pave the road for identifying innovative greening strategies and interventions that can improve mental health in dementia.

Greenness and neuropsychiatric symptoms in dementia / Tondelli, Manuela; Chiari, Annalisa; Vinceti, Giulia; Galli, Chiara; Salemme, Simone; Filippini, Tommaso; Carbone, Chiara; Minafra, Claudia; De Luca, Claudia; Prandi, Riccardo; Tondelli, Simona; Zamboni, Giovanna. - In: ENVIRONMENTAL RESEARCH. - ISSN 1096-0953. - ELETTRONICO. - 242:(2024), pp. 117652.1-117652.7. [10.1016/j.envres.2023.117652]

Greenness and neuropsychiatric symptoms in dementia

De Luca, Claudia
Conceptualization
;
Tondelli, Simona
Conceptualization
;
2024

Abstract

Objectives: It is acknowledged that living in a green environment may help mental well-being and this may be especially true for vulnerable people. However, the relationship between greenness and neuropsychiatric symptoms in dementia has not been explored yet. Methods: We collected clinical, neuropsychiatric, and residential data from subjects with dementia living in the province of Modena, Northern Italy. Neuropsychiatric symptoms were measured with the Neuropsychiatry Inventory, a questionnaire administered to the caregiver who assesses the presence and severity of neuropsychiatric symptoms, including delusions, hallucinations, agitation/aggression, dysphoria/depression, anxiety, euphoria/elation, apathy/indifference, disinhibition, irritability/lability, aberrant motor behaviors, sleep disturbances, and appetite/eating changes. Normalized Difference Vegetation Index (NDVI) was used as a proxy of greenness. Regression models were constructed to study the association between greenness and neuropsychiatric features. Results: 155 patients with dementia were recruited. We found that greenness is variably associated with the risk of having neuropsychiatric symptoms. The risk of apathy was lower with lower levels of greenness (OR = 0.42, 95% CI 0.19-0.91 for NDVI below the median value). The risk of psychosis was higher with lower levels of greenness but with more imprecise values (OR = 1.77, 95% CI 0.84-3.73 for NDVI below the median value). Conclusion: Our results suggest a possible association between greenness and neuropsychiatric symptoms in people with dementia. If replicated in larger samples, these findings will pave the road for identifying innovative greening strategies and interventions that can improve mental health in dementia.
2024
Greenness and neuropsychiatric symptoms in dementia / Tondelli, Manuela; Chiari, Annalisa; Vinceti, Giulia; Galli, Chiara; Salemme, Simone; Filippini, Tommaso; Carbone, Chiara; Minafra, Claudia; De Luca, Claudia; Prandi, Riccardo; Tondelli, Simona; Zamboni, Giovanna. - In: ENVIRONMENTAL RESEARCH. - ISSN 1096-0953. - ELETTRONICO. - 242:(2024), pp. 117652.1-117652.7. [10.1016/j.envres.2023.117652]
Tondelli, Manuela; Chiari, Annalisa; Vinceti, Giulia; Galli, Chiara; Salemme, Simone; Filippini, Tommaso; Carbone, Chiara; Minafra, Claudia; De Luca, Claudia; Prandi, Riccardo; Tondelli, Simona; Zamboni, Giovanna
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/951342
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