Juvenile Idiopathic Arthritis (JIA) is a paediatric disease of unknown aetiology potentially leading to biomechanical alterations due to local damage of joints. After assessing its reliability, a patient-specific musculoskeletal model of the lower limb was used to investigate the link between joint loading and disease activity in a cohort of JIA children with ankle involvement. We observed a common strategy aiming at protecting the affected ankles with consequent overloading of hip and knee. When quantified at patient specific level, this strategy might allow to identify those cases where a localised steroid injection might not be sufficient to induce remission.
O 104 - MRI-based musculoskeletal models for the quantification of gait in children with Juvenile Idiopathic Arthritis / Montefiori E.; Modenese L.; Di Marco R.; Magni-Manzoni S.; Malattia C.; Petrarca M.; Ronchetti A.; van Dijkhuizen P.; Viceconti M.; Mazza C.. - In: GAIT & POSTURE. - ISSN 0966-6362. - ELETTRONICO. - 65:(2018), pp. 216-218. [10.1016/j.gaitpost.2018.06.139]
O 104 - MRI-based musculoskeletal models for the quantification of gait in children with Juvenile Idiopathic Arthritis
Modenese L.;Ronchetti A.;Viceconti M.;
2018
Abstract
Juvenile Idiopathic Arthritis (JIA) is a paediatric disease of unknown aetiology potentially leading to biomechanical alterations due to local damage of joints. After assessing its reliability, a patient-specific musculoskeletal model of the lower limb was used to investigate the link between joint loading and disease activity in a cohort of JIA children with ankle involvement. We observed a common strategy aiming at protecting the affected ankles with consequent overloading of hip and knee. When quantified at patient specific level, this strategy might allow to identify those cases where a localised steroid injection might not be sufficient to induce remission.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
