Juvenile Idiopathic Arthritis (JIA) is a paediatric disease of unknown aetiology potentially leading to biomechanical alterations due to local damage of joints. After assessing its reliability, a patient-specific musculoskeletal model of the lower limb was used to investigate the link between joint loading and disease activity in a cohort of JIA children with ankle involvement. We observed a common strategy aiming at protecting the affected ankles with consequent overloading of hip and knee. When quantified at patient specific level, this strategy might allow to identify those cases where a localised steroid injection might not be sufficient to induce remission.
Montefiori E., Modenese L., Di Marco R., Magni-Manzoni S., Malattia C., Petrarca M., et al. (2018). O 104 - MRI-based musculoskeletal models for the quantification of gait in children with Juvenile Idiopathic Arthritis. GAIT & POSTURE, 65, 216-218 [10.1016/j.gaitpost.2018.06.139].
O 104 - MRI-based musculoskeletal models for the quantification of gait in children with Juvenile Idiopathic Arthritis
Modenese L.;Ronchetti A.;Viceconti M.;
2018
Abstract
Juvenile Idiopathic Arthritis (JIA) is a paediatric disease of unknown aetiology potentially leading to biomechanical alterations due to local damage of joints. After assessing its reliability, a patient-specific musculoskeletal model of the lower limb was used to investigate the link between joint loading and disease activity in a cohort of JIA children with ankle involvement. We observed a common strategy aiming at protecting the affected ankles with consequent overloading of hip and knee. When quantified at patient specific level, this strategy might allow to identify those cases where a localised steroid injection might not be sufficient to induce remission.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
