Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

Sartelli, Massimo; Barie, Philip S.; Coccolini, Federico; Abbas, Mohamed; Abbo, Lilian M.; Abdukhalilova, Gulnora K.; Abraham, Yishak; Abubakar, Salisu; Abu-Zidan, Fikri M.; Adebisi, Yusuff Adebayo; Adamou, Harissou; Afandiyeva, Gulara; Agastra, Ervis; Alfouzan, Wadha A.; Al-Hasan, Majdi N.; Ali, Sajjad; Ali, Syed Muhammad; Allaw, Fatima; Allwell-Brown, Gbemisola; Amir, Afreenish; Amponsah, Obed Kwabena Offe; Al Omari, Abdelkarim; Ansaloni, Luca; Ansari, Shamshul; Arauz, Ana Belen; Augustin, Goran; Awazi, Bih; Azfar, Mohammad; Bah, Mamadou Saliou Bailo; Bala, Miklosh; Banagala, Anura S. K.; Baral, Suman; Bassetti, Matteo; Bavestrello, Luis; Beilman, Gregory; Bekele, Kebebe; Benboubker, Moussa; Beović, Bojana; Bergamasco, Maria Daniela; Bertagnolio, Silvia; Biffl, Walter L.; Blot, Stijn; Boermeester, Marja A.; Bonomo, Robert A.; Brink, Adrian; Brusaferro, Silvio; Butemba, Jonathan; Caínzos, Miguel A.; Camacho-Ortiz, Adrian; Canton, Rafael; Cascio, Antonio; Cassini, Alessandro; Cástro-Sanchez, Enrique; Catarci, Marco; Catena, Rodolfo; Chamani-Tabriz, Leili; Chandy, Sujith J.; Charani, Esmita; Cheadle, William G.; Chebet, Diana; Chikowe, Ibrahim; Chiara, Francesca; Cheng, Vincent Chi-Chung; Chioti, Anna; Cocuz, Maria Elena; Coimbra, Raul; Cortese, Francesco; Cui, Yunfeng; Czepiel, Jacek; Dasic, Mira; de Francisco Serpa, Nataliya; de Jonge, Stijn W.; Delibegovic, Samir; Dellinger, E. Patchen; Demetrashvili, Zaza; De Palma, Alessandra; De Silva, Danushka; De Simone, Belinda; De Waele, Jan; Dhingra, Sameer; Diaz, Jose J.; Dima, Claudia; Dirani, Natalia; Dodoo, Cornelius C.; Dorj, Gereltuya; Duane, Therese M.; Eckmann, Christian; Egyir, Beverly; Elmangory, Mutasim M.; Enani, Mushira A.; Ergonul, Onder; Escalera-Antezana, Juan Pablo; Escandon, Kevin; Ettu, Abdul-Wahab Omo-ope; Fadare, Joseph O.; Fantoni, Massimo; Farahbakhsh, Mohammad; Faro, Mario Paulo; Ferreres, Alberto; Flocco, Gianina; Foianini, Esteban; Fry, Donald E.; Garcia, Alberto Federico; Gerardi, Chiara; Ghannam, Wagih; Giamarellou, Helen; Glushkova, Natalya; Gkiokas, George; Goff, Debra A.; Gomi, Harumi; Gottfredsson, Magnus; Griffiths, Ewen A.; Guerra Gronerth, Rosio Isabel; Guirao, Xavier; Gupta, Yogesh K.; Halle-Ekane, Gregory; Hansen, Sonja; Haque, Mainul; Hardcastle, Timothy C.; Hayman, David T. S.; Hecker, Andreas; Hell, Markus; Vanessa P., Ho; Hodonou, Adrien M.; Isik, Arda; Islam, Salequl; Itani, Kamal M. F.; Jaidane, Nadia; Jammer, Ib; Jenkins, David R.; Kamara, Ibrahim Franklyn; Kanj, Souha S.; Jumbam, Desmond; Keikha, Masoud; Khanna, Ashish K.; Khanna, Sahil; Kapoor, Gaetanjali; Kapoor, Garima; Kariuki, Samuel; Khamis, Faryal; Khokha, Vladimir; Kiggundu, Reuben; Kiguba, Ronald; Kim, Hong Bin; Kim, Peter K.; Kirkpatrick, Andrew W.; Kluger, Yoram; Wen-Chien, Ko; Kok, Kenneth Y. Y.; Kotecha, Vihar; Kouma, Ibrahima; Kovacevic, Bojan; Krasniqi, Jehona; Krutova, Marcela; Kryvoruchko, Igor; Kullar, Ravina; Labi, Kwaku A.; Labricciosa, Francesco M.; Lakoh, Sulaiman; Lakatos, Botond; Lansang, Mary Ann D.; Laxminarayan, Ramanan; Lee, Young Ran; Leone, Marc; Leppaniemi, Ari; Hara, Gabriel Levy; Litvin, Andrey; Lohsiriwat, Varut; Machain, Gustavo M.; Mahomoodally, Fawzi; Maier, Ronald V.; Majumder, Md Anwarul Azim; Malama, Sydney; Manasa, Justen; Manchanda, Vikas; Manzano-Nunez, Ramiro; Martínez-Martínez, Luis; Martin-Loeches, Ignacio; Marwah, Sanjay; Maseda, Emilio; Mathewos, Maleda; Maves, Ryan C.; Mcnamara, Deborah; Memish, Ziad; Mertz, Dominik; Mishra, Shyam Kumar; Montravers, Philippe; Moro, Maria Luisa; Mossialos, Elias; Motta, Fabrizio; Mudenda, Steward; Mugabi, Patrick; Mugisha, Mc Juan Muco; Mylonakis, Eleftherios; Napolitano, Lena M.; Nathwani, Dilip; Nkamba, Leontine; Nsutebu, Emmanuel Fru; O’Connor, Donal B.; Ogunsola, Sade; Jensen, Peter Østrup; Ordoñez, Juliana Maria; Ordoñez, Carlos A.; Ottolino, Pablo; Ouedraogo, Abdoul-Salam; Paiva, José Artur; Palmieri, Miriam; Pan, Angelo; Pant, Narayan; Panyko, Arpád; Paolillo, Ciro; Patel, Jay; Pea, Federico; Petrone, Patrizio; Petrosillo, Nicola; Pintar, Tadeja; Plaudis, Haralds; Podda, Mauro; Ponce-de-Leon, Alfredo; Powell, Susan L.; Puello-Guerrero, Adrián; Pulcini, Celine; Rasa, Kemal; Regimbeau, Jean-Marc; Rello, Jordi; Retamozo-Palacios, Manuel Renato; Reynolds-Campbell, Glendee; Ribeiro, Julival; Rickard, Jennifer; Rocha-Pereira, Nuno; Rosenthal, Victor D.; Rossolini, Gian Maria; Rwegerera, Godfrey M.; Rwigamba, Megan; Sabbatucci, Michela; Saladžinskas, Žilvinas; Salama, Rasha E.; Sali, Tondore; Salile, Samson Sahile; Sall, Ibrahima; Kafil, Hossein Samadi; Sakakushev, Boris E.; Sawyer, Robert G.; Scatizzi, Marco; Seni, Jeremiah; Septimus, Edward J.; Sganga, Gabriele; Shabanzadeh, Daniel Mønsted; Shelat, Vishal G.; Shibabaw, Agumas; Somville, Francis; Souf, Selma; Stefani, Stefania; Tacconelli, Evelina; Tan, Buon Kim; Tattevin, Pierre; Rodriguez-Taveras, Carlos; Telles, João Paulo; Téllez-Almenares, Orlando; Tessier, Jeffrey; Thang, Nguyen Toan; Timmermann, Cristian; Timsit, Jean-François; Tochie, Joel Noutakdie; Tolonen, Matti; Trueba, Gabriel; Tsioutis, Constantinos; Tumietto, Fabio; Tuon, Felipe Francisco; Ulrych, Jan; Uranues, Selman; van Dongen, Maarten; van Goor, Harry; Velmahos, George C.; Vereczkei, Andras; Viaggi, Bruno; Viale, Pierluigi; Vila, Jordi; Voss, Andreas; Vraneš, Jasmina; Watkins, Richard R.; Wanjiru-Korir, Nyambura; Waworuntu, Olivia; Wechsler-Fördös, Agnes; Yadgarova, Klara; Yahaya, Mohammed; Yahya, Ali I.; Xiao, Yonghong; Zakaria, Andee Dzulkarnaen; Zakrison, Tanya L.; Zamora Mesia, Victor; Siquini, Walter; Darzi, Ara; Pagani, Leonardo; Catena, Fausto

doi:10.1186/s13017-023-00518-3

: Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice.

Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action / Sartelli, Massimo; Barie, Philip S.; Coccolini, Federico; Abbas, Mohamed; Abbo, Lilian M.; Abdukhalilova, Gulnora K.; Abraham, Yishak; Abubakar, Salisu; Abu-Zidan, Fikri M.; Adebisi, Yusuff Adebayo; Adamou, Harissou; Afandiyeva, Gulara; Agastra, Ervis; Alfouzan, Wadha A.; Al-Hasan, Majdi N.; Ali, Sajjad; Ali, Syed Muhammad; Allaw, Fatima; Allwell-Brown, Gbemisola; Amir, Afreenish; Amponsah, Obed Kwabena Offe; Al Omari, Abdelkarim; Ansaloni, Luca; Ansari, Shamshul; Arauz, Ana Belen; Augustin, Goran; Awazi, Bih; Azfar, Mohammad; Bah, Mamadou Saliou Bailo; Bala, Miklosh; Banagala, Anura S. K.; Baral, Suman; Bassetti, Matteo; Bavestrello, Luis; Beilman, Gregory; Bekele, Kebebe; Benboubker, Moussa; Beović, Bojana; Bergamasco, Maria Daniela; Bertagnolio, Silvia; Biffl, Walter L.; Blot, Stijn; Boermeester, Marja A.; Bonomo, Robert A.; Brink, Adrian; Brusaferro, Silvio; Butemba, Jonathan; Caínzos, Miguel A.; Camacho-Ortiz, Adrian; Canton, Rafael; Cascio, Antonio; Cassini, Alessandro; Cástro-Sanchez, Enrique; Catarci, Marco; Catena, Rodolfo; Chamani-Tabriz, Leili; Chandy, Sujith J.; Charani, Esmita; Cheadle, William G.; Chebet, Diana; Chikowe, Ibrahim; Chiara, Francesca; Cheng, Vincent Chi-Chung; Chioti, Anna; Cocuz, Maria Elena; Coimbra, Raul; Cortese, Francesco; Cui, Yunfeng; Czepiel, Jacek; Dasic, Mira; de Francisco Serpa, Nataliya; de Jonge, Stijn W.; Delibegovic, Samir; Dellinger, E. Patchen; Demetrashvili, Zaza; De Palma, Alessandra; De Silva, Danushka; De Simone, Belinda; De Waele, Jan; Dhingra, Sameer; Diaz, Jose J.; Dima, Claudia; Dirani, Natalia; Dodoo, Cornelius C.; Dorj, Gereltuya; Duane, Therese M.; Eckmann, Christian; Egyir, Beverly; Elmangory, Mutasim M.; Enani, Mushira A.; Ergonul, Onder; Escalera-Antezana, Juan Pablo; Escandon, Kevin; Ettu, Abdul-Wahab Omo-ope; Fadare, Joseph O.; Fantoni, Massimo; Farahbakhsh, Mohammad; Faro, Mario Paulo; Ferreres, Alberto; Flocco, Gianina; Foianini, Esteban; Fry, Donald E.; Garcia, Alberto Federico; Gerardi, Chiara; Ghannam, Wagih; Giamarellou, Helen; Glushkova, Natalya; Gkiokas, George; Goff, Debra A.; Gomi, Harumi; Gottfredsson, Magnus; Griffiths, Ewen A.; Guerra Gronerth, Rosio Isabel; Guirao, Xavier; Gupta, Yogesh K.; Halle-Ekane, Gregory; Hansen, Sonja; Haque, Mainul; Hardcastle, Timothy C.; Hayman, David T. S.; Hecker, Andreas; Hell, Markus; Ho, Vanessa P.; Hodonou, Adrien M.; Isik, Arda; Islam, Salequl; Itani, Kamal M. F.; Jaidane, Nadia; Jammer, Ib; Jenkins, David R.; Kamara, Ibrahim Franklyn; Kanj, Souha S.; Jumbam, Desmond; Keikha, Masoud; Khanna, Ashish K.; Khanna, Sahil; Kapoor, Gaetanjali; Kapoor, Garima; Kariuki, Samuel; Khamis, Faryal; Khokha, Vladimir; Kiggundu, Reuben; Kiguba, Ronald; Kim, Hong Bin; Kim, Peter K.; Kirkpatrick, Andrew W.; Kluger, Yoram; Ko, Wen-Chien; Kok, Kenneth Y. Y.; Kotecha, Vihar; Kouma, Ibrahima; Kovacevic, Bojan; Krasniqi, Jehona; Krutova, Marcela; Kryvoruchko, Igor; Kullar, Ravina; Labi, Kwaku A.; Labricciosa, Francesco M.; Lakoh, Sulaiman; Lakatos, Botond; Lansang, Mary Ann D.; Laxminarayan, Ramanan; Lee, Young Ran; Leone, Marc; Leppaniemi, Ari; Hara, Gabriel Levy; Litvin, Andrey; Lohsiriwat, Varut; Machain, Gustavo M.; Mahomoodally, Fawzi; Maier, Ronald V.; Majumder, Md Anwarul Azim; Malama, Sydney; Manasa, Justen; Manchanda, Vikas; Manzano-Nunez, Ramiro; Martínez-Martínez, Luis; Martin-Loeches, Ignacio; Marwah, Sanjay; Maseda, Emilio; Mathewos, Maleda; Maves, Ryan C.; McNamara, Deborah; Memish, Ziad; Mertz, Dominik; Mishra, Shyam Kumar; Montravers, Philippe; Moro, Maria Luisa; Mossialos, Elias; Motta, Fabrizio; Mudenda, Steward; Mugabi, Patrick; Mugisha, Mc Juan Muco; Mylonakis, Eleftherios; Napolitano, Lena M.; Nathwani, Dilip; Nkamba, Leontine; Nsutebu, Emmanuel Fru; O’Connor, Donal B.; Ogunsola, Sade; Jensen, Peter Østrup; Ordoñez, Juliana Maria; Ordoñez, Carlos A.; Ottolino, Pablo; Ouedraogo, Abdoul-Salam; Paiva, José Artur; Palmieri, Miriam; Pan, Angelo; Pant, Narayan; Panyko, Arpád; Paolillo, Ciro; Patel, Jay; Pea, Federico; Petrone, Patrizio; Petrosillo, Nicola; Pintar, Tadeja; Plaudis, Haralds; Podda, Mauro; Ponce-de-Leon, Alfredo; Powell, Susan L.; Puello-Guerrero, Adrián; Pulcini, Celine; Rasa, Kemal; Regimbeau, Jean-Marc; Rello, Jordi; Retamozo-Palacios, Manuel Renato; Reynolds-Campbell, Glendee; Ribeiro, Julival; Rickard, Jennifer; Rocha-Pereira, Nuno; Rosenthal, Victor D.; Rossolini, Gian Maria; Rwegerera, Godfrey M.; Rwigamba, Megan; Sabbatucci, Michela; Saladžinskas, Žilvinas; Salama, Rasha E.; Sali, Tondore; Salile, Samson Sahile; Sall, Ibrahima; Kafil, Hossein Samadi; Sakakushev, Boris E.; Sawyer, Robert G.; Scatizzi, Marco; Seni, Jeremiah; Septimus, Edward J.; Sganga, Gabriele; Shabanzadeh, Daniel Mønsted; Shelat, Vishal G.; Shibabaw, Agumas; Somville, Francis; Souf, Selma; Stefani, Stefania; Tacconelli, Evelina; Tan, Buon Kim; Tattevin, Pierre; Rodriguez-Taveras, Carlos; Telles, João Paulo; Téllez-Almenares, Orlando; Tessier, Jeffrey; Thang, Nguyen Toan; Timmermann, Cristian; Timsit, Jean-François; Tochie, Joel Noutakdie; Tolonen, Matti; Trueba, Gabriel; Tsioutis, Constantinos; Tumietto, Fabio; Tuon, Felipe Francisco; Ulrych, Jan; Uranues, Selman; van Dongen, Maarten; van Goor, Harry; Velmahos, George C.; Vereczkei, Andras; Viaggi, Bruno; Viale, Pierluigi; Vila, Jordi; Voss, Andreas; Vraneš, Jasmina; Watkins, Richard R.; Wanjiru-Korir, Nyambura; Waworuntu, Olivia; Wechsler-Fördös, Agnes; Yadgarova, Klara; Yahaya, Mohammed; Yahya, Ali I.; Xiao, Yonghong; Zakaria, Andee Dzulkarnaen; Zakrison, Tanya L.; Zamora Mesia, Victor; Siquini, Walter; Darzi, Ara; Pagani, Leonardo; Catena, Fausto. - In: WORLD JOURNAL OF EMERGENCY SURGERY. - ISSN 1749-7922. - ELETTRONICO. - 10.1186/s13017-023-00518-3:1(2023), pp. 50.1-50.35. [10.1186/s13017-023-00518-3]