Background and Objective: BorderlinePersonalityDisorder(BPD)isunder-investigatedinFirstEpisodePsychosis(FEP).BPDpsychoticmanifestationsandmoodchangesarealsodifficulttodif-ferentiatefromfirstepisodeaffectivepsychosis.Theaimofthisstudywastocomparesociode-mographicandclinicalfeaturesbetweenFEPpatientswithBPDvs.BipolarDisorder(BD)orMajorDepressiveDisorder(MDD)bothatbaselineandacrossa2-yearfollow-upperiod.Methods:224FEPparticipants(49withBPD,93withBDand82withMDD)completedtheHealthoftheNationOutcomeScale(HoNOS),thePositiveAndNegativeSyndromeScale(PANSS)andtheGlobalAssessmentofFunctioning(GAF)scale.Psychiatricdiagnosiswasreformulatedattheendofourfollow-up.Inter-groupcomparisonswereanalyzedusingtheKruskal-WallisortheChi-squaretest.Amixed-designANOVAmodelwasalsoperformedtoassessthetemporalstabilityofclinicalscoreswithinandbetweenthe3subgroups.Results:ComparedtoFEP/BDsubjectsatbaseline,FEP/BPDpatientsshowedhigherdepressivesymptomseverityandlowerexcitementseverity.ComparedtoFEP/MDDatentry,theyhadahigherprevalencerateofsubstanceabuse,alowerinterpersonalimpairmentandashorterDUP.
Borderline personality disorder vs. mood disorders: clinical comparisons in young people treated within an “Early Intervention” service for first episode psychosis.
Lorenzo Pelizza
Primo
;Arianna Biancalani;Lorenzo Gammino;Marco Menchetti.Ultimo
2023
Abstract
Background and Objective: BorderlinePersonalityDisorder(BPD)isunder-investigatedinFirstEpisodePsychosis(FEP).BPDpsychoticmanifestationsandmoodchangesarealsodifficulttodif-ferentiatefromfirstepisodeaffectivepsychosis.Theaimofthisstudywastocomparesociode-mographicandclinicalfeaturesbetweenFEPpatientswithBPDvs.BipolarDisorder(BD)orMajorDepressiveDisorder(MDD)bothatbaselineandacrossa2-yearfollow-upperiod.Methods:224FEPparticipants(49withBPD,93withBDand82withMDD)completedtheHealthoftheNationOutcomeScale(HoNOS),thePositiveAndNegativeSyndromeScale(PANSS)andtheGlobalAssessmentofFunctioning(GAF)scale.Psychiatricdiagnosiswasreformulatedattheendofourfollow-up.Inter-groupcomparisonswereanalyzedusingtheKruskal-WallisortheChi-squaretest.Amixed-designANOVAmodelwasalsoperformedtoassessthetemporalstabilityofclinicalscoreswithinandbetweenthe3subgroups.Results:ComparedtoFEP/BDsubjectsatbaseline,FEP/BPDpatientsshowedhigherdepressivesymptomseverityandlowerexcitementseverity.ComparedtoFEP/MDDatentry,theyhadahigherprevalencerateofsubstanceabuse,alowerinterpersonalimpairmentandashorterDUP.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
