Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a product containing beta-mannanase produced by a non-genetically modified strain of Aspergillus niger (CBS 120604). The commercial name is Nutrixtend Optim and it is intended to be used as a zootechnical feed additive for all poultry for fattening. Based on a tolerance trial in chickens for fattening and the no observed adverse effect level identified in a subchronic oral toxicity study in rats, the additive was considered safe for all poultry for fattening. The Panel concluded that the use of the product as a feed additive does not give rise to concerns for consumers and the environment. The additive is considered an irritant to skin and eyes and a dermal sensitiser. Due to the proteinaceous nature of the active substance, it is also considered a respiratory sensitiser. The Panel concludes that the additive has the potential to be efficacious as a zootechnical additive at the level of inclusion in feed of chickens for fattening of 30 U beta-mannanase/kg complete feed. This conclusion was extrapolated to all poultry for fattening. (c) 2023 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH on behalf of European Food Safety Authority.

Bampidis V., Azimonti G., Bastos M.d.L., Christensen H., Dusemund B., Durjava M., et al. (2023). Safety and efficacy of a feed additive consisting of β-mannanase produced by Aspergillus niger CBS 120604 (Nutrixtend Optim) for use in all poultry for fattening (Kerry Ingredients & Flavours Ltd). EFSA JOURNAL, 21(6), 1-13 [10.2903/j.efsa.2023.8045].

Safety and efficacy of a feed additive consisting of β-mannanase produced by Aspergillus niger CBS 120604 (Nutrixtend Optim) for use in all poultry for fattening (Kerry Ingredients & Flavours Ltd)

Martelli G.;
2023

Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a product containing beta-mannanase produced by a non-genetically modified strain of Aspergillus niger (CBS 120604). The commercial name is Nutrixtend Optim and it is intended to be used as a zootechnical feed additive for all poultry for fattening. Based on a tolerance trial in chickens for fattening and the no observed adverse effect level identified in a subchronic oral toxicity study in rats, the additive was considered safe for all poultry for fattening. The Panel concluded that the use of the product as a feed additive does not give rise to concerns for consumers and the environment. The additive is considered an irritant to skin and eyes and a dermal sensitiser. Due to the proteinaceous nature of the active substance, it is also considered a respiratory sensitiser. The Panel concludes that the additive has the potential to be efficacious as a zootechnical additive at the level of inclusion in feed of chickens for fattening of 30 U beta-mannanase/kg complete feed. This conclusion was extrapolated to all poultry for fattening. (c) 2023 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH on behalf of European Food Safety Authority.
2023
Bampidis V., Azimonti G., Bastos M.d.L., Christensen H., Dusemund B., Durjava M., et al. (2023). Safety and efficacy of a feed additive consisting of β-mannanase produced by Aspergillus niger CBS 120604 (Nutrixtend Optim) for use in all poultry for fattening (Kerry Ingredients & Flavours Ltd). EFSA JOURNAL, 21(6), 1-13 [10.2903/j.efsa.2023.8045].
Bampidis V.; Azimonti G.; Bastos M.d.L.; Christensen H.; Dusemund B.; Durjava M.; Kouba M.; López-Alonso M.; López Puente S.; Marcon F.; Mayo B.; Pech...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/936873
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