There are several types of immunological tests available for the diagnosis and management of Helicobacter pylori infection. Most commercially available serological kits use the enzyme linked immunosorbent assay (ELISA) test format. Originally the kits used crude antigen preparations although many of the newer kits use a more purified antigen preparation, with often increased specificity but lower sensitivity. Near patient test kits are based either on latex agglutination or immunochromatography. Generally they have low sensitivities compared with laboratory tests. Western blotting, ELISA, and recombinant immunoblot assays (RIBA) have also been developed into commercially available kits and can be used to indicate the presence of specific virulence markers. An antigen detection kit has been developed for the detection of Helicobacter pylori in faeces. Immunological reagents have also been combined with other diagnostic modalities to develop immunohistochemical stains and DNA immunoassays.

Vaira D., Holton J., Menegatti M., Ricci C., Landi F., Ali' A., et al. (1999). New immunological assays for the diagnosis of Helicobacter pylori infection. GUT, 45(1), I23-I27 [10.1136/gut.45.2008.i23].

New immunological assays for the diagnosis of Helicobacter pylori infection

Vaira D.;Ricci C.;Ali' A.;Gatta L.;Berardi S.;
1999

Abstract

There are several types of immunological tests available for the diagnosis and management of Helicobacter pylori infection. Most commercially available serological kits use the enzyme linked immunosorbent assay (ELISA) test format. Originally the kits used crude antigen preparations although many of the newer kits use a more purified antigen preparation, with often increased specificity but lower sensitivity. Near patient test kits are based either on latex agglutination or immunochromatography. Generally they have low sensitivities compared with laboratory tests. Western blotting, ELISA, and recombinant immunoblot assays (RIBA) have also been developed into commercially available kits and can be used to indicate the presence of specific virulence markers. An antigen detection kit has been developed for the detection of Helicobacter pylori in faeces. Immunological reagents have also been combined with other diagnostic modalities to develop immunohistochemical stains and DNA immunoassays.
1999
GUT
Vaira D., Holton J., Menegatti M., Ricci C., Landi F., Ali' A., et al. (1999). New immunological assays for the diagnosis of Helicobacter pylori infection. GUT, 45(1), I23-I27 [10.1136/gut.45.2008.i23].
Vaira D.; Holton J.; Menegatti M.; Ricci C.; Landi F.; Ali' A.; Gatta L.; Acciardi C.; Farinelli S.; Crosatti M.; Berardi S.; Miglioli M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/936362
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