The present study has compared two different LC-MS related instruments: a triple quadrupole mass spectrometry (QqQ) and a high resolution full scan acquisition on orbitral trap (LTQ-Orbitrap). Advantages, limitations, and drawbacks of the different tested technologies have been discussed taking into account their validated performances (specificity, sensitivity, dynamic range, linearity …) and their potential in the scope of a multiresidue monitoring.
Compared analytical development and validation based on liquid chromatography coupled to tandem or high resolution mass spectrometry for measuring perfluorinated compounds in milk
BARBAROSSA, ANDREA;PAGLIUCA, GIAMPIERO;
2010
Abstract
The present study has compared two different LC-MS related instruments: a triple quadrupole mass spectrometry (QqQ) and a high resolution full scan acquisition on orbitral trap (LTQ-Orbitrap). Advantages, limitations, and drawbacks of the different tested technologies have been discussed taking into account their validated performances (specificity, sensitivity, dynamic range, linearity …) and their potential in the scope of a multiresidue monitoring.File in questo prodotto:
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