The present study has compared two different LC-MS related instruments: a triple quadrupole mass spectrometry (QqQ) and a high resolution full scan acquisition on orbitral trap (LTQ-Orbitrap). Advantages, limitations, and drawbacks of the different tested technologies have been discussed taking into account their validated performances (specificity, sensitivity, dynamic range, linearity …) and their potential in the scope of a multiresidue monitoring.
Veyrand B, Kadar H, Barbarossa A, Durand S, Marchand P, Antignac JP, et al. (2010). Compared analytical development and validation based on liquid chromatography coupled to tandem or high resolution mass spectrometry for measuring perfluorinated compounds in milk.
Compared analytical development and validation based on liquid chromatography coupled to tandem or high resolution mass spectrometry for measuring perfluorinated compounds in milk
BARBAROSSA, ANDREA;PAGLIUCA, GIAMPIERO;
2010
Abstract
The present study has compared two different LC-MS related instruments: a triple quadrupole mass spectrometry (QqQ) and a high resolution full scan acquisition on orbitral trap (LTQ-Orbitrap). Advantages, limitations, and drawbacks of the different tested technologies have been discussed taking into account their validated performances (specificity, sensitivity, dynamic range, linearity …) and their potential in the scope of a multiresidue monitoring.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
