GASTon: A Graph-Exploration System for Indexing, Annotating and Visualizing PubMed Articles to Enhance the Analysis of Social deTerminants of Health

Many works have shown associations between social determinants of health (SDoH) –the social circumstances in which people live– and health-related outcomes. However, the lack of SDoH data increases the challenges in measuring and understanding their effect on people’s health and health systems. In this paper, we present GASTon, a system for the indexing, annotation, and graph-based rendering of PubMed information to enable the search and retrieval of SDoHs in scientific literature. Our work provides a way to associate specific concepts with peer-reviewed articles to simplify the search for social factors. It builds a knowledge graph based on PubMed publications and associates them with concepts extracted from the Unified Medical Language System (UMLS) Metathesaurus. GASTon allows a full-text search and graph-based navigation and supports an overview of the concepts and related publications. Moreover, the architecture allows scale-up thanks to its containerized nature and parallelizat ion capabilities. The system is open-source under the Apache V2 license.