A potential role of gastrointestinal microbiota in irritable bowel syndrome, obesity, food antigen-related adverse responses and diabetes has been indicated. In many diseases an altered gastrointestinal microbiota is related to the reduction of the population of bifidobacteria. Predicting the distribution and colonization of bifidobacteria in the gastrointestinal tract is increasingly warranted. The interacting strain-inherent and cultivation-dependent effects on microbial cell surface behavior may have broad consequences for the fate and ecology of bifidobacteria, therefore surface properties may determine an isolate's physical fate. In bifidobacteria the effects of environmental factors on the variability of cell-wall protein expression (BIFOP) and gastrointestinal tract adhesion properties have been studied.We have verified in vitro that environmental factors, which can possibly be present in vivo, are able to modify BIFOPs expression and the adhesion potential of bifidobacterial species, suggesting their important role in modulating the col

HOST-MICROBIOTA INTERACTIONS: ENVIRONMENTAL STRESS AFFECTING CELL-WALL PROTEIN EXPRESSION IN BIFIDOBACTERIUM SPP.

MATTARELLI, PAOLA;BIAVATI, BRUNO;SGORBATI, BARBARA
2010

Abstract

A potential role of gastrointestinal microbiota in irritable bowel syndrome, obesity, food antigen-related adverse responses and diabetes has been indicated. In many diseases an altered gastrointestinal microbiota is related to the reduction of the population of bifidobacteria. Predicting the distribution and colonization of bifidobacteria in the gastrointestinal tract is increasingly warranted. The interacting strain-inherent and cultivation-dependent effects on microbial cell surface behavior may have broad consequences for the fate and ecology of bifidobacteria, therefore surface properties may determine an isolate's physical fate. In bifidobacteria the effects of environmental factors on the variability of cell-wall protein expression (BIFOP) and gastrointestinal tract adhesion properties have been studied.We have verified in vitro that environmental factors, which can possibly be present in vivo, are able to modify BIFOPs expression and the adhesion potential of bifidobacterial species, suggesting their important role in modulating the col
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Mattarelli P.; Tacconi S.; Biavati B.; Sgorbati B.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/92340
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