Breast cancer metastases to the gastrointestinal tract are very rare occurrences. Among the histological subtypes of breast cancer, invasive lobular carcinomas have a high capacity of metastasis to uncommon sites including the stomach. Conversely, there has not been sufficient evidence supporting the gastric metastasis of invasive ductal carcinoma. Herein, we report a unique case of metastatic ductal breast carcinoma mimicking primary linitis plastica in a male patient, particularly focusing on the clinical and pathological features of presentation. Moreover, we propose a immunohistochemical panel of selected antibodies including those for cytokeratin 20, cytokeratin 7, estrogen receptor, progesterone receptor, E-cadherin, gross cystic disease fluid protein 15, and GATA binding protein 3 for an accurate differential diagnosis.

Ductal breast carcinoma metastatic to the stomach resembling primary linitis plastica in a male patient / Ricciuti B.; Leonardi G.C.; Ravaioli N.; De Giglio A.; Brambilla M.; Prosperi E.; Ribacchi F.; Meacci M.; Crino L.; Maiettini D.; Chiari R.; Metro G.. - In: JOURNAL OF BREAST CANCER. - ISSN 1738-6756. - ELETTRONICO. - 19:3(2016), pp. 324-329. [10.4048/jbc.2016.19.3.324]

Ductal breast carcinoma metastatic to the stomach resembling primary linitis plastica in a male patient

Ricciuti B.;De Giglio A.;
2016

Abstract

Breast cancer metastases to the gastrointestinal tract are very rare occurrences. Among the histological subtypes of breast cancer, invasive lobular carcinomas have a high capacity of metastasis to uncommon sites including the stomach. Conversely, there has not been sufficient evidence supporting the gastric metastasis of invasive ductal carcinoma. Herein, we report a unique case of metastatic ductal breast carcinoma mimicking primary linitis plastica in a male patient, particularly focusing on the clinical and pathological features of presentation. Moreover, we propose a immunohistochemical panel of selected antibodies including those for cytokeratin 20, cytokeratin 7, estrogen receptor, progesterone receptor, E-cadherin, gross cystic disease fluid protein 15, and GATA binding protein 3 for an accurate differential diagnosis.
2016
Ductal breast carcinoma metastatic to the stomach resembling primary linitis plastica in a male patient / Ricciuti B.; Leonardi G.C.; Ravaioli N.; De Giglio A.; Brambilla M.; Prosperi E.; Ribacchi F.; Meacci M.; Crino L.; Maiettini D.; Chiari R.; Metro G.. - In: JOURNAL OF BREAST CANCER. - ISSN 1738-6756. - ELETTRONICO. - 19:3(2016), pp. 324-329. [10.4048/jbc.2016.19.3.324]
Ricciuti B.; Leonardi G.C.; Ravaioli N.; De Giglio A.; Brambilla M.; Prosperi E.; Ribacchi F.; Meacci M.; Crino L.; Maiettini D.; Chiari R.; Metro G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/918672
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