This review is intended to give a brief summary of some of the more recent developments in the synthesis of p-amino acids and asubstituted amino acids. The first part is concerned with an overview of the naturally occurring compounds containing p-amino acids. The second part summarises results on the synthesis of natural and unnatural p-amino acids, by routes involving the enzymatic resolution of racemic mixtures, the intermediary preparation of perhydropyrimidin-4-ones and the conjugate addition of ammonia equivalents to a, P-unsaturated esters and imides which are all topics near to the scientific interest of the authors. For a more complete overview of the methods developed to obtain enantiomerically pure p-amino acids, including hydrogenation of 3-aminoacrylates and nucleophilic addition of enolates to imines, see two recent excellent reviews.

Cardillo G., Tomasini C. (1996). Asymmetric synthesis of β-amino acids and α-substituted β-amino acids. CHEMICAL SOCIETY REVIEWS, 25(2), 117-128 [10.1039/CS9962500117].

Asymmetric synthesis of β-amino acids and α-substituted β-amino acids

Tomasini C.
Ultimo
1996

Abstract

This review is intended to give a brief summary of some of the more recent developments in the synthesis of p-amino acids and asubstituted amino acids. The first part is concerned with an overview of the naturally occurring compounds containing p-amino acids. The second part summarises results on the synthesis of natural and unnatural p-amino acids, by routes involving the enzymatic resolution of racemic mixtures, the intermediary preparation of perhydropyrimidin-4-ones and the conjugate addition of ammonia equivalents to a, P-unsaturated esters and imides which are all topics near to the scientific interest of the authors. For a more complete overview of the methods developed to obtain enantiomerically pure p-amino acids, including hydrogenation of 3-aminoacrylates and nucleophilic addition of enolates to imines, see two recent excellent reviews.
1996
Cardillo G., Tomasini C. (1996). Asymmetric synthesis of β-amino acids and α-substituted β-amino acids. CHEMICAL SOCIETY REVIEWS, 25(2), 117-128 [10.1039/CS9962500117].
Cardillo G.; Tomasini C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/916670
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