The asymmetric 1,4 addition of PhMgCl, MeMgBr and allylMgBr to chiral imides 1 has been studied under various conditions. The presence of a Lewis acid, as AlMe2Cl, affords an enhanced diastereoselectivity favouring the formation of the product derived from the attack on the re face. The 1,4 addition of allyl diisopropoxyborate to imides 1 has also been analysed. Copyright © 1996 Elsevier Science Ltd.

Bongini A., Cardillo G., Mingardi A., Tomasini C. (1996). Asymmetric 1,4 addition of grignard reagents to chiral α,β-unsaturated imides in the presence of Lewis acids. TETRAHEDRON-ASYMMETRY, 7(5), 1457-1466 [10.1016/0957-4166(96)00163-2].

Asymmetric 1,4 addition of grignard reagents to chiral α,β-unsaturated imides in the presence of Lewis acids

Bongini A.;Mingardi A.;Tomasini C.
1996

Abstract

The asymmetric 1,4 addition of PhMgCl, MeMgBr and allylMgBr to chiral imides 1 has been studied under various conditions. The presence of a Lewis acid, as AlMe2Cl, affords an enhanced diastereoselectivity favouring the formation of the product derived from the attack on the re face. The 1,4 addition of allyl diisopropoxyborate to imides 1 has also been analysed. Copyright © 1996 Elsevier Science Ltd.
1996
Bongini A., Cardillo G., Mingardi A., Tomasini C. (1996). Asymmetric 1,4 addition of grignard reagents to chiral α,β-unsaturated imides in the presence of Lewis acids. TETRAHEDRON-ASYMMETRY, 7(5), 1457-1466 [10.1016/0957-4166(96)00163-2].
Bongini A.; Cardillo G.; Mingardi A.; Tomasini C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/916666
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