OBJECTIVES: Our goal was to report outcomes of the endovascular repair of urgent thoracoabdominal aortic aneurysms (TAAAs) using the Cook Zenith t-Branch off-the-shelf multibranched endograft.METHODS: Between 2010 and 2020, we collected patients with TAAA5 who received an urgent endovascular repair using the Cook Zenith t-Branch (had a rupture, symptoms or diameter >80 mm). Thirty-day mortality, spinal cord ischaemia (SCI) and clinical success were assessed as early outcomes. Freedom from reintervention, target visceral vessel patency and survival were considered during follow-up.RESULTS: Sixty-five cases were managed using the Cook Zenith t-Branch for 27 (42%) TAAA ruptures, 8 (12%) symptomatic TAAAs and 30 (46%) asymptomatic TAAAs with a diameter >80 mm. Crawford's extent I-II-III and IV were noted in 54 (83%) and 11 (17%), respectively. Eleven (17%) patients had SCI with 3 (5%) cases of permanent paraplegia. Postoperative dialysis (P = 0.04) and ruptured TAAAs (P = 0.05) were associated with SCI. Sixteen (25%) patients had reinterventions within the first 30 days postoperatively. The 30-day mortality was 14% (9). Ruptured TAAAs (P = 0.05) and technical failures (P = 0.01) were correlated with in-hospital mortality. Clinical success was 78% (51 patients). The mean follow-up was 18 +/- 14 months. Survival at 24 months was 47% with no late TAAA-related deaths. Patients with ruptured TAAAs had lower survival than those who did not have ruptured TAAAs (52% vs 60% at 1 year; P = 0.05). Target visceral vessel patency and freedom from reintervention at 24 months were 89% and 60%, respectively.CONCLUSIONS: An off-the-shelf multibranched endograft is safe and effective for treating urgent TAAAs. Postoperative SCI and 30-day mortality are satisfactory for this challenging clinical scenario. The early reintervention rate is not negligible. Midterm survival is low, especially in patients with a ruptured TAAA; therefore, accurate patient selection is mandatory.

Gallitto, E., Faggioli, G., Spath, P., Pini, R., Mascoli, C., Logiacco, A., et al. (2022). Urgent endovascular repair of thoracoabdominal aneurysms using an off-the-shelf multibranched endograft. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 61(5), 1087-1096 [10.1093/ejcts/ezab553].

Urgent endovascular repair of thoracoabdominal aneurysms using an off-the-shelf multibranched endograft

Gallitto, Enrico;Faggioli, Gianluca;Spath, Paolo;Pini, Rodolfo;Mascoli, Chiara;Logiacco, Antonino;Gargiulo, Mauro
2022

Abstract

OBJECTIVES: Our goal was to report outcomes of the endovascular repair of urgent thoracoabdominal aortic aneurysms (TAAAs) using the Cook Zenith t-Branch off-the-shelf multibranched endograft.METHODS: Between 2010 and 2020, we collected patients with TAAA5 who received an urgent endovascular repair using the Cook Zenith t-Branch (had a rupture, symptoms or diameter >80 mm). Thirty-day mortality, spinal cord ischaemia (SCI) and clinical success were assessed as early outcomes. Freedom from reintervention, target visceral vessel patency and survival were considered during follow-up.RESULTS: Sixty-five cases were managed using the Cook Zenith t-Branch for 27 (42%) TAAA ruptures, 8 (12%) symptomatic TAAAs and 30 (46%) asymptomatic TAAAs with a diameter >80 mm. Crawford's extent I-II-III and IV were noted in 54 (83%) and 11 (17%), respectively. Eleven (17%) patients had SCI with 3 (5%) cases of permanent paraplegia. Postoperative dialysis (P = 0.04) and ruptured TAAAs (P = 0.05) were associated with SCI. Sixteen (25%) patients had reinterventions within the first 30 days postoperatively. The 30-day mortality was 14% (9). Ruptured TAAAs (P = 0.05) and technical failures (P = 0.01) were correlated with in-hospital mortality. Clinical success was 78% (51 patients). The mean follow-up was 18 +/- 14 months. Survival at 24 months was 47% with no late TAAA-related deaths. Patients with ruptured TAAAs had lower survival than those who did not have ruptured TAAAs (52% vs 60% at 1 year; P = 0.05). Target visceral vessel patency and freedom from reintervention at 24 months were 89% and 60%, respectively.CONCLUSIONS: An off-the-shelf multibranched endograft is safe and effective for treating urgent TAAAs. Postoperative SCI and 30-day mortality are satisfactory for this challenging clinical scenario. The early reintervention rate is not negligible. Midterm survival is low, especially in patients with a ruptured TAAA; therefore, accurate patient selection is mandatory.
2022
Gallitto, E., Faggioli, G., Spath, P., Pini, R., Mascoli, C., Logiacco, A., et al. (2022). Urgent endovascular repair of thoracoabdominal aneurysms using an off-the-shelf multibranched endograft. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 61(5), 1087-1096 [10.1093/ejcts/ezab553].
Gallitto, Enrico; Faggioli, Gianluca; Spath, Paolo; Pini, Rodolfo; Mascoli, Chiara; Logiacco, Antonino; Gargiulo, Mauro
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/915703
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