The production of fine chemicals, new materials and products from renewable feedstocks represents a continuous challenge. Several procedures have been reported in the literature or patented in the last decade for the main biomass components: carbohydrates (75%), lignins (20%), fats and oils (5%) [1]. Regarding oleochemical developments, the oxidative cleavage of unsaturated fatty acids to produce dicarboxylic acids, hydroxy acids, and amino acids has received great attention in the last decade [2]. Two main oleochemical products obtained by the cleavage of unsaturated fatty acids are sebacic acid and azelaic acid. Azelaic acid (AzA) is a naturally occurring saturated nine carbon atom dicarboxylic acid found in whole grains, wheat, rye and barley [2], first detected in rancid fats. It can be formed endogenously from substrates such as longer-chain dicarboxylic acids and processes like the metabolism of oleic acid, and ψ-oxidation of monocarboxylic acids. The azelaic acid market is predicted to reach USD 160 million by 2023 and the applications include pharmacological ingredients, polymers, plastics, lubricants and materials for electronics [3]. The aim of the present review is to highlight the potential of azelaic acid as powerful building block for the synthesis of bio-based and biodegradable polymers, with a special emphasis on the green synthetic routes, embracing both chemical and enzymatic methods.

Anamaria Todea, Caterina Deganutti, Mariachiara Spennato, Fioretta Asaro, Guglielmo Zingone, Tiziana Milizia, et al. (2021). Azelaic Acid: A Bio-Based Building Block for Biodegradable Polymers. POLYMERS, 13(23), 1-22 [10.3390/polym13234091].

Azelaic Acid: A Bio-Based Building Block for Biodegradable Polymers

Mariachiara Spennato;
2021

Abstract

The production of fine chemicals, new materials and products from renewable feedstocks represents a continuous challenge. Several procedures have been reported in the literature or patented in the last decade for the main biomass components: carbohydrates (75%), lignins (20%), fats and oils (5%) [1]. Regarding oleochemical developments, the oxidative cleavage of unsaturated fatty acids to produce dicarboxylic acids, hydroxy acids, and amino acids has received great attention in the last decade [2]. Two main oleochemical products obtained by the cleavage of unsaturated fatty acids are sebacic acid and azelaic acid. Azelaic acid (AzA) is a naturally occurring saturated nine carbon atom dicarboxylic acid found in whole grains, wheat, rye and barley [2], first detected in rancid fats. It can be formed endogenously from substrates such as longer-chain dicarboxylic acids and processes like the metabolism of oleic acid, and ψ-oxidation of monocarboxylic acids. The azelaic acid market is predicted to reach USD 160 million by 2023 and the applications include pharmacological ingredients, polymers, plastics, lubricants and materials for electronics [3]. The aim of the present review is to highlight the potential of azelaic acid as powerful building block for the synthesis of bio-based and biodegradable polymers, with a special emphasis on the green synthetic routes, embracing both chemical and enzymatic methods.
2021
Anamaria Todea, Caterina Deganutti, Mariachiara Spennato, Fioretta Asaro, Guglielmo Zingone, Tiziana Milizia, et al. (2021). Azelaic Acid: A Bio-Based Building Block for Biodegradable Polymers. POLYMERS, 13(23), 1-22 [10.3390/polym13234091].
Anamaria Todea; Caterina Deganutti; Mariachiara Spennato; Fioretta Asaro; Guglielmo Zingone; Tiziana Milizia; Lucia Gardossi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/913566
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