We report a general, scalable, and convenient photochemical process for diversities of distal oxygenated nitriles from corresponding less-strained ketoxime esters allowing one-step introductions of ether and cyano groups, which avoids the utilization of toxic cyanide reagents. A wide range of ketoxime esters involving five-membered to eight-membered cycloketoxime esters and linear ketoxime esters participate smoothly under operately simple and mild conditions, affording structurally variable ring-opening products.
Wang M., Chen C., Ma M., Zhao B., Shi Z. (2022). Photoinduced Etherification of Less-Strained Cycloketoxime Esters Enabled by C-C Bond Cleavage. JOURNAL OF ORGANIC CHEMISTRY, 87(5), 3577-3585 [10.1021/acs.joc.1c03131].
Photoinduced Etherification of Less-Strained Cycloketoxime Esters Enabled by C-C Bond Cleavage
Zhao B.
;Shi Z.
2022
Abstract
We report a general, scalable, and convenient photochemical process for diversities of distal oxygenated nitriles from corresponding less-strained ketoxime esters allowing one-step introductions of ether and cyano groups, which avoids the utilization of toxic cyanide reagents. A wide range of ketoxime esters involving five-membered to eight-membered cycloketoxime esters and linear ketoxime esters participate smoothly under operately simple and mild conditions, affording structurally variable ring-opening products.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
