The simple, commercially available ZnBr2 has been successfully employed as a highly efficient and chemoselective catalyst for the dehydrogenative borylation of terminal alkynes with HBpin under mild conditions. It shows a good tolerance toward various functional groups such as aryl, alkyl, heteroaryl, etc. The plausible reaction mechanism has been investigated based on the corresponding stoichiometric experiments and DFT calculations.
Luo M., Qin Y., Chen X., Xiao Q., Zhao B., Yao W., et al. (2021). ZnBr2-Catalyzed Dehydrogenative Borylation of Terminal Alkynes. JOURNAL OF ORGANIC CHEMISTRY, 86(23), 16666-16674 [10.1021/acs.joc.1c01936].
ZnBr2-Catalyzed Dehydrogenative Borylation of Terminal Alkynes
Xiao Q.;Zhao B.;
2021
Abstract
The simple, commercially available ZnBr2 has been successfully employed as a highly efficient and chemoselective catalyst for the dehydrogenative borylation of terminal alkynes with HBpin under mild conditions. It shows a good tolerance toward various functional groups such as aryl, alkyl, heteroaryl, etc. The plausible reaction mechanism has been investigated based on the corresponding stoichiometric experiments and DFT calculations.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
