Psychiatric disorder as clinical presentation of primary Sjögren's syndrome: Two case reports

Psychiatric disorders in primary Sjögren's syndrome constitute a possible clinical reality that each practitioner must be able to recognise and treat. In this article, two case reports of mental disorder as clinical presentation of primary Sjögren's syndrome are presented, suggesting that psychiatric manifestations in primary Sjögren's syndrome can occur not only during its longitudinal course, but also at the onset of the autoimmune syndrome. A better adapted prescription of corticosteroids and/or immunosuppressive agents (together with specific psychotropic treatments) can induce rapid relief of mental symptoms. © 2010 Pelizza et al; licensee BioMed Central Ltd.