In recent years, gastric ulceration has been recognized as a common, possibly performancelimiting disease, of adult horses. The aim of this study was to compare endoscopic features, histological diagnosis, and mRNA levels of various cytokines (TNF-α, IL-1β, and IL-13) from horse gastric biopsies. Eleven horses suffering from equine gastric ulcer syndrome and seven horses with normal histological gastric features were assessed. No correlation between endoscopic features and histology (i.e., the gold standard) was observed. Based on histological diagnosis, a significant (p<0.05) increase in cytokine mRNA levels (specifically, TNF-α and IL-13) was observed in horses affected by equine ulcerative gastric syndrome
Pietra M., Morini M., Perfetti G, Spadari A., Vigo P., Peli A. (2010). Comparison of endoscopy, histology, and cytokine mRNA of the equine gastric mucosa. VETERINARY RESEARCH COMMUNICATIONS, 34(Suppl. 1), 121-124 [10.1007/s11259-010-9401-6].
Comparison of endoscopy, histology, and cytokine mRNA of the equine gastric mucosa.
PIETRA, MARCO;MORINI, MARIA;SPADARI, ALESSANDRO;VIGO, PAOLO;PELI, ANGELO
2010
Abstract
In recent years, gastric ulceration has been recognized as a common, possibly performancelimiting disease, of adult horses. The aim of this study was to compare endoscopic features, histological diagnosis, and mRNA levels of various cytokines (TNF-α, IL-1β, and IL-13) from horse gastric biopsies. Eleven horses suffering from equine gastric ulcer syndrome and seven horses with normal histological gastric features were assessed. No correlation between endoscopic features and histology (i.e., the gold standard) was observed. Based on histological diagnosis, a significant (p<0.05) increase in cytokine mRNA levels (specifically, TNF-α and IL-13) was observed in horses affected by equine ulcerative gastric syndromeI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
