Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.
Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual / Alfonso Iovieno; Simonetta Piana; Laura Chiesi; Cristina Fodero; FONTANA L. - In: INTERNATIONAL OPHTHALMOLOGY. - ISSN 0165-5701. - ELETTRONICO. - 38:(2018), pp. 1347-1350. [10.1007/s10792-017-0573-8]
Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual
FONTANA L
2018
Abstract
Purpose: To describe a case of bilateral conjunctival and cervical human papillomavirus (HPV)-related squamous neoplasia. Case description: A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease-free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade cervical squamous dysplasia. HPV infection with genotypes 16 (right eye), 11 and 39 (left eye) and 39 (uterine cervix) was also detected. Conclusion: Simultaneous uterine and conjunctival HPV-related squamous neoplasia can occur in immunocompetent individuals. Auto-inoculation and repeated exposure to HPV could explain coexistence of different genotypes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
