The large demand for DNA analysis calls for the development of portable, low-cost, easy-to-perform assays. We developed and performed preliminary assessments of an integrable biosensor for the direct detection of DNA sequences through capacitance measurements. The device behaves consistently with a proposed electrical model and it reliably detects DNA hybridization with high specificity. We have also verified the reproducibility of the experimental results and the reusability of the DNA biosensor.
A biosensor for direct detection of DNA sequences based on capacitance measurements
C. Guiducci
Primo
Investigation
;C. Stagni;G. ZuccheriInvestigation
;A. Bogliolo;L. Benini;
2002
Abstract
The large demand for DNA analysis calls for the development of portable, low-cost, easy-to-perform assays. We developed and performed preliminary assessments of an integrable biosensor for the direct detection of DNA sequences through capacitance measurements. The device behaves consistently with a proposed electrical model and it reliably detects DNA hybridization with high specificity. We have also verified the reproducibility of the experimental results and the reusability of the DNA biosensor.File in questo prodotto:
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