Liver cirrhosis is an established high-risk factor for HCC and the majority of patients diagnosed with HCC have cirrhosis. However, HCC also arises in non-cirrhotic livers in approximately 20 %of all cases. HCC in non-cirrhotic patients is often clinically silent and surveillance is usually not recommended. HCC is often diagnosed at an advanced stage in these patients. Current information about HCC in patients with non-cirrhotic liver is limited. Here we review the current knowledge on epidemiology, clinical features and imaging features of those patiens.
Hepatocellular carcinoma in the non-cirrhotic liver / Dong Y.; Wang W.-P.; Lee W.J.; Meloni M.F.; Clevert D.-A.; Chammas M.C.; Tannapfel A.; Forgione A.; Piscaglia F.; Dietrich C.F.. - In: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION. - ISSN 1386-0291. - STAMPA. - 80:4(2022), pp. 423-436. [10.3233/CH-211309]
Hepatocellular carcinoma in the non-cirrhotic liver
Dong Y.;Forgione A.;Piscaglia F.;
2022
Abstract
Liver cirrhosis is an established high-risk factor for HCC and the majority of patients diagnosed with HCC have cirrhosis. However, HCC also arises in non-cirrhotic livers in approximately 20 %of all cases. HCC in non-cirrhotic patients is often clinically silent and surveillance is usually not recommended. HCC is often diagnosed at an advanced stage in these patients. Current information about HCC in patients with non-cirrhotic liver is limited. Here we review the current knowledge on epidemiology, clinical features and imaging features of those patiens.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
