Flutamide (FLU) is a non-steroidal antiandrogen drug approved for the treatment of advanced prostate cancer. While this indication limits the use to male patients, FLU is widely prescribed to women, off-label, for the treatment of polycystic ovary syndrome (POCS) related hirsutism and acne. According to the literature, its assumption is associated with a higher incidence of adverse events in women than in male patients.

Flutamide-induced hepatotoxicity: ethical and scientific issues

Giorgetti, A;
2017

Abstract

Flutamide (FLU) is a non-steroidal antiandrogen drug approved for the treatment of advanced prostate cancer. While this indication limits the use to male patients, FLU is widely prescribed to women, off-label, for the treatment of polycystic ovary syndrome (POCS) related hirsutism and acne. According to the literature, its assumption is associated with a higher incidence of adverse events in women than in male patients.
2017
Giorgetti, R; di Muzio, M; Giorgetti, A; Girolami, D; Borgia, L; Tagliabracci, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/903854
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