Cyberknife robotic radiosurgery (RRS) provides single-session high-dose radiotherapy of brain tumors with a steep dose gradient and precise real-time image-guided motion correction. Although RRS appears to cause more radiation necrosis (RN), the radiometabolic changes after RRS have not been fully clarified. 18F-FET-PET/CT is used to differentiate recurrent tumor (RT) from RN after radiosurgery when MRI findings are indecisive. We explored the usefulness of dynamic parameters derived from 18F-FET PET in differentiating RT from RN after Cyberknife treatment in a single-center study population.

Dynamic 18F-FET PET/CT to differentiate recurrent primary brain tumor and brain metastases from radiation necrosis after single-session robotic radiosurgery / Lim, Winna; Acker, Gueliz; Hardt, Juliane; Kufeld, Markus; Kluge, Anne; Brenner, Winfried; Conti, Alfredo; Budach, Volker; Vajkoczy, Peter; Senger, Carolin; Prasad, Vikas. - In: CANCER TREATMENT AND RESEARCH COMMUNICATIONS. - ISSN 2468-2942. - STAMPA. - 32:(2022), pp. 100583.1-100583.9. [10.1016/j.ctarc.2022.100583]

Dynamic 18F-FET PET/CT to differentiate recurrent primary brain tumor and brain metastases from radiation necrosis after single-session robotic radiosurgery

Conti, Alfredo;
2022

Abstract

Cyberknife robotic radiosurgery (RRS) provides single-session high-dose radiotherapy of brain tumors with a steep dose gradient and precise real-time image-guided motion correction. Although RRS appears to cause more radiation necrosis (RN), the radiometabolic changes after RRS have not been fully clarified. 18F-FET-PET/CT is used to differentiate recurrent tumor (RT) from RN after radiosurgery when MRI findings are indecisive. We explored the usefulness of dynamic parameters derived from 18F-FET PET in differentiating RT from RN after Cyberknife treatment in a single-center study population.
2022
Dynamic 18F-FET PET/CT to differentiate recurrent primary brain tumor and brain metastases from radiation necrosis after single-session robotic radiosurgery / Lim, Winna; Acker, Gueliz; Hardt, Juliane; Kufeld, Markus; Kluge, Anne; Brenner, Winfried; Conti, Alfredo; Budach, Volker; Vajkoczy, Peter; Senger, Carolin; Prasad, Vikas. - In: CANCER TREATMENT AND RESEARCH COMMUNICATIONS. - ISSN 2468-2942. - STAMPA. - 32:(2022), pp. 100583.1-100583.9. [10.1016/j.ctarc.2022.100583]
Lim, Winna; Acker, Gueliz; Hardt, Juliane; Kufeld, Markus; Kluge, Anne; Brenner, Winfried; Conti, Alfredo; Budach, Volker; Vajkoczy, Peter; Senger, Carolin; Prasad, Vikas
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/902033
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