Organocatalysis - catalysis mediated by small chiral organic molecules - is a powerful technology for enantioselective synthesis, and has extensive applications in traditional ionic, two-electron-pair reactivity domains. Recently, organocatalysis has been successfully combined with photochemical reactivity to unlock previously inaccessible reaction pathways, thereby creating new synthetic opportunities. Here we describe the historical context, scientific reasoning and landmark discoveries that were essential in expanding the functions of organocatalysis to include one-electron-mediated chemistry and excited-state reactivity.
Silvi M., Melchiorre P. (2018). Enhancing the potential of enantioselective organocatalysis with light. NATURE, 554(7690), 41-49 [10.1038/nature25175].
Enhancing the potential of enantioselective organocatalysis with light
Melchiorre P.
Ultimo
Conceptualization
2018
Abstract
Organocatalysis - catalysis mediated by small chiral organic molecules - is a powerful technology for enantioselective synthesis, and has extensive applications in traditional ionic, two-electron-pair reactivity domains. Recently, organocatalysis has been successfully combined with photochemical reactivity to unlock previously inaccessible reaction pathways, thereby creating new synthetic opportunities. Here we describe the historical context, scientific reasoning and landmark discoveries that were essential in expanding the functions of organocatalysis to include one-electron-mediated chemistry and excited-state reactivity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
