This study was designed to demonstrate that MSPc of T. denticola stimulates release of proinflammatory mediators in primary human monocytes. Our results indicate that T. denticola MSPc, at concentrations ranging from 100 ng/mL to 1.0 mug/mL, activates a proinflammatory response in primary human monocytes.
P. Gaibani, F. Caroli, C. Nucci, V. Sambri (2010). Major surface protein complex of Treponema denticola induces the production of tumor necrosis factor alpha, interleukin-1beta, interleukin-6 and matrix metalloproteinase 9by primary human peripheral blood monocytes. JOURNAL OF PERIODONTAL RESEARCH, 45, 361-366 [10.1111/j.1600-0765.2009.01246.x].
Major surface protein complex of Treponema denticola induces the production of tumor necrosis factor alpha, interleukin-1beta, interleukin-6 and matrix metalloproteinase 9by primary human peripheral blood monocytes.
GAIBANI, PAOLO;NUCCI, CESARE;SAMBRI, VITTORIO
2010
Abstract
This study was designed to demonstrate that MSPc of T. denticola stimulates release of proinflammatory mediators in primary human monocytes. Our results indicate that T. denticola MSPc, at concentrations ranging from 100 ng/mL to 1.0 mug/mL, activates a proinflammatory response in primary human monocytes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
