Flexible microelectrode array based on PEDOT:PSS for neural recording and stimulation

Flexible microelectrode arrays placed on the surface of the brain cortex are promising tools for treating neurological deficits and restoring lost functionalities. Modern microfabrication techniques offer great possibilities to achieve high spatial and temporal resolution, but the device performances are ultimately determined by the material chosen as the biotic/abiotic interface. The conductive polymer poly(3,4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) is a favorable material to use for this scope, due to its biocompatibility, long-term stability, and large charge injection capacity. Our research aims to realize an optimized device with flexible mechanical properties and low-impedance electrodes enabling efficient recording and stimulation of neural activity.