Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.
Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective / Martina Rossi; Paolo Blasi. - In: FRONTIERS IN MEDICAL TECHNOLOGY. - ISSN 2673-3129. - ELETTRONICO. - 4:(2022), pp. 909943.1-909943.7. [10.3389/fmedt.2022.909943]
Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective
Martina RossiPrimo
Writing – Original Draft Preparation
;Paolo Blasi
Ultimo
Writing – Review & Editing
2022
Abstract
Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.| File | Dimensione | Formato | |
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Front. Med. Technol. 4 (2022) 909943.pdf
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