Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.
Martina Rossi, Paolo Blasi (2022). Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective. FRONTIERS IN MEDICAL TECHNOLOGY, 4, 1-7 [10.3389/fmedt.2022.909943].
Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective
Martina RossiPrimo
Writing – Original Draft Preparation
;Paolo Blasi
Ultimo
Writing – Review & Editing
2022
Abstract
Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.File in questo prodotto:
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