Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.

Multicellular Tumor Spheroids in Nanomedicine Research: A Perspective

Martina Rossi
Primo
Writing – Original Draft Preparation
;
Paolo Blasi
Ultimo
Writing – Review & Editing
2022

Abstract

Multicellular tumor spheroids are largely exploited in cancer research since they are more predictive than bi-dimensional cell cultures. Nanomedicine would benefit from the integration of this three-dimensional in vitro model in screening protocols. In this brief work, we discuss some of the issues that cancer nanomedicine will need to consider in the switch from bi-dimensional to three-dimensional multicellular tumor spheroid models.
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Front. Med. Technol. 4 (2022) 909943.pdf

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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/893847
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