Apathy, mood depression and extrapyramidal signs consisting of akinesia, amimia. gait apraxia, slight rigidity and tremor were induced in 10 patients by long-term treatment with flunarizine for trivial complaints. These symptoms suggest a mild antidopaminergic activity of flunarizine. Long-term administration of flunarizine should be avoided particularly in the elderly and in patients with cxtrapyramidal disorders. © 1988 S. Karger AG, Basel.
Lugaresi A., Montagna P., Gallassi R., Lugaresi E. (1988). Extrapyramidal syndrome and depression induced by flunarizine. EUROPEAN NEUROLOGY, 28(4), 208-211 [10.1159/000116268].
Extrapyramidal syndrome and depression induced by flunarizine
Lugaresi A.Primo
Investigation
;Montagna P.;Gallassi R.;Lugaresi E.
1988
Abstract
Apathy, mood depression and extrapyramidal signs consisting of akinesia, amimia. gait apraxia, slight rigidity and tremor were induced in 10 patients by long-term treatment with flunarizine for trivial complaints. These symptoms suggest a mild antidopaminergic activity of flunarizine. Long-term administration of flunarizine should be avoided particularly in the elderly and in patients with cxtrapyramidal disorders. © 1988 S. Karger AG, Basel.File in questo prodotto:
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