Irradiation with red light is able to improve yields and shorten the reaction time in enzymatic reactions. A commercially available laccase from Trametes versicolor, used in conjunction with a catalytic amount of TEMPO (20 mol%), was irradiated under red light (630 nm) for the clean oxidation of benzylic alcohols and amines in a faster reaction compared to the one conducted in the dark, affording the desired product in excellent yields (up to 99%) using air as the terminal oxidant. The observed acceleration is due to the strongest oxidation ability of laccase, in its excited state, towards TEMPO.

Acceleration of oxidation promoted by laccase irradiation with red light

Valentina Giraldi;Marianna Marchini;Matteo Di Giosia;Andrea Gualandi;Martina Cirillo;Matteo Calvaresi;Paola Ceroni;Daria Giacomini
;
Pier Giorgio Cozzi
2022

Abstract

Irradiation with red light is able to improve yields and shorten the reaction time in enzymatic reactions. A commercially available laccase from Trametes versicolor, used in conjunction with a catalytic amount of TEMPO (20 mol%), was irradiated under red light (630 nm) for the clean oxidation of benzylic alcohols and amines in a faster reaction compared to the one conducted in the dark, affording the desired product in excellent yields (up to 99%) using air as the terminal oxidant. The observed acceleration is due to the strongest oxidation ability of laccase, in its excited state, towards TEMPO.
Valentina Giraldi; Marianna Marchini; Matteo Di Giosia; Andrea Gualandi; Martina Cirillo; Matteo Calvaresi; Paola Ceroni; Daria Giacomini; Pier Giorgio Cozzi
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11585/890072
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