SIR, in a recent article published in Brain (Hicks et al., 2009), while confirming our finding that myoblasts from patients affected by Ullrich congenital muscular dystrophy (UCMD) display a latentmitochondrial dysfunction that can be unmasked by the addition of the F1FO ATPase inhibitor oligomycin (Angelin et al., 2007), Hicks et al. conclude that ‘PTP dysregulation may be a particular characteristic of the state of these cells in culture and is not specific to the collagen VI defect’. .............................
Bernardi P, Bonaldo P, Maraldi NM, Merlini L, Sabatelli P. (2009). On the pathogenesis of collagen VI muscular dystrophies--comment on article of Hicks et al. BRAIN, 132, 1-2 [10.1093/brain/awp021].
On the pathogenesis of collagen VI muscular dystrophies--comment on article of Hicks et al.
MARALDI, NADIR;
2009
Abstract
SIR, in a recent article published in Brain (Hicks et al., 2009), while confirming our finding that myoblasts from patients affected by Ullrich congenital muscular dystrophy (UCMD) display a latentmitochondrial dysfunction that can be unmasked by the addition of the F1FO ATPase inhibitor oligomycin (Angelin et al., 2007), Hicks et al. conclude that ‘PTP dysregulation may be a particular characteristic of the state of these cells in culture and is not specific to the collagen VI defect’. .............................I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
