We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.

BRAF-mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis

Abbati F.;Dika E.;
2021

Abstract

We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.
2021
Abbati F.; Altimari A.; Corti B.; Dika E.; Sperandi F.; Melotti B.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/885875
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