We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.
BRAF-mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis
Abbati F.;Dika E.;
2021
Abstract
We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.File in questo prodotto:
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Clinical Case Reports - 2021 - Abbati - BRAF‐mutated malignant melanoma with chondrosarcomatous differentiation in inguinal.pdf
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